inhib_
Iron
- Joined
- Aug 8, 2026
- Posts
- 7
- Reputation
- 10
HYPERPHOSPHATEMIA
Erdafitinhib inhibits the FGFR in the kidneys which blocks normal signalling by FGF23, that usually instructs the renal tubules to excrete phosphate but now instead the kidneys reabsorb more phosphate back into the bloodstream, raising serum phosphate levels and thus causing hyperphosphatemia. We can mitigate this in nang ways such as...
BINDERS
Contrary to popular belief, Selevamer carbonate is not the most effective phosphate binder, a much better option would be
LANTHANUM CARBONATE
Which as shown in this study is the superior opt
View attachment 5492336
with the usual dose being either 500mg,750mg or 1000mg taken 3 times a day distributed across meals depending on the phosphate levels of the food/drink.
DIET
We ideally want to limit phosphate intake to 600-800mg daily, we can achieve this by
ADDITIVES
Check food labels for
-Phosphoric acid
-Calcium phosphate
-Sodium phosphate
-Potassium phosphate
And Various phosphate-based food additives
Ensure to limit/avoid food or drink containing this
Avoid fast food, bottled ice teas, cola drinks and packaged convenience meals
CUT OUT
Pre packaged ice teas
Alcohol
Enhanced waters/sports drinks
Literally all sodas apart from some upcoming
Oily fish (salmon mackerel sardines) and shellfish
processed meats ( deli slices, bacon, hot dogs, sausages)
Organ meats (liver, kidney etc)
Oatmeal
Brown rice
Wild rice
Baking goods containing baking powder
Bran cereals
Processed cheeses ( American slices, cheese spreads)
yogurt and ice cream
Peas
Beans
Dried nuts
Peanut butter
Chocolate
LIMIT
Whole eggs
Milk
Hard cheeses ( Swiss, Cheddar etc)
Nuts
Seeds
Lentils
ENJOY
Water
7UP/Sprite
Home brewed tea and coffee
Flavoured waters without phosphate ingredients
Noodles
Pasta
White rice
Grits
Couscous
White bread
Lean cuts of fresh chicken, turkey, beef, pork and fresh white fish (unbreaded)
Cream cheese
Cottage cheese
Sour cream
Sherbet
Fresh apples, berries, grapes, carrots, cucumber, popcorn and pretzels
CHECKING LEVELS
You'll need a phosphate blood test which can be performed by your local doctor and can be bought out of pocket without a referral
If under 16 simply find a site where they will only ask for ID if they suspect you look under 16 and not needed on hand. Only applies for people who's parents will be suspicious due to phosphate levels or not allow the blood test.
For the UK you can use onedaytests.com
SUPPLEMENTS AND PRODUCTS TO AVOID
Check all supplements for phosphates
Vitamin D supplements
phosphate salts/any standalone phosphorus dietary supplements
Indigestion remedies or antacids that contain phosphorus
Laxatives or enemas/bowel preparations containing phosphate
THANKS FOR READING AND STAY SAFE
Erdafitinhib inhibits the FGFR in the kidneys which blocks normal signalling by FGF23, that usually instructs the renal tubules to excrete phosphate but now instead the kidneys reabsorb more phosphate back into the bloodstream, raising serum phosphate levels and thus causing hyperphosphatemia. We can mitigate this in nang ways such as...
BINDERS
Contrary to popular belief, Selevamer carbonate is not the most effective phosphate binder, a much better option would be
LANTHANUM CARBONATE
Which as shown in this study is the superior opt
with the usual dose being either 500mg,750mg or 1000mg taken 3 times a day distributed across meals depending on the phosphate levels of the food/drink.
DIET
We ideally want to limit phosphate intake to 600-800mg daily, we can achieve this by
ADDITIVES
Check food labels for
-Phosphoric acid
-Calcium phosphate
-Sodium phosphate
-Potassium phosphate
And Various phosphate-based food additives
Ensure to limit/avoid food or drink containing this
Avoid fast food, bottled ice teas, cola drinks and packaged convenience meals
CUT OUT
Pre packaged ice teas
Alcohol
Enhanced waters/sports drinks
Literally all sodas apart from some upcoming
Oily fish (salmon mackerel sardines) and shellfish
processed meats ( deli slices, bacon, hot dogs, sausages)
Organ meats (liver, kidney etc)
Oatmeal
Brown rice
Wild rice
Baking goods containing baking powder
Bran cereals
Processed cheeses ( American slices, cheese spreads)
yogurt and ice cream
Peas
Beans
Dried nuts
Peanut butter
Chocolate
LIMIT
Whole eggs
Milk
Hard cheeses ( Swiss, Cheddar etc)
Nuts
Seeds
Lentils
ENJOY
Water
7UP/Sprite
Home brewed tea and coffee
Flavoured waters without phosphate ingredients
Noodles
Pasta
White rice
Grits
Couscous
White bread
Lean cuts of fresh chicken, turkey, beef, pork and fresh white fish (unbreaded)
Cream cheese
Cottage cheese
Sour cream
Sherbet
Fresh apples, berries, grapes, carrots, cucumber, popcorn and pretzels
CHECKING LEVELS
You'll need a phosphate blood test which can be performed by your local doctor and can be bought out of pocket without a referral
If under 16 simply find a site where they will only ask for ID if they suspect you look under 16 and not needed on hand. Only applies for people who's parents will be suspicious due to phosphate levels or not allow the blood test.
For the UK you can use onedaytests.com
SUPPLEMENTS AND PRODUCTS TO AVOID
Check all supplements for phosphates
Vitamin D supplements
phosphate salts/any standalone phosphorus dietary supplements
Indigestion remedies or antacids that contain phosphorus
Laxatives or enemas/bowel preparations containing phosphate
THANKS FOR READING AND STAY SAFE
