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sandcelmuttcel
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The purpose of this study was to illustrate the effects of growth hormone (GH) therapy and fixed functional appliance treatment in a 13-year-old Class II malocclusion patient without GH deficiency. GH has been shown to effectively increase endochondral growth and induce a more prognathic skeletal pattern. Although a major concern in Class II retrognathic patients is chin deficiency, long-term studies have shown that the mandibular growth enhancement effects of functional appliances are clinically insignificant. This case report demonstrates that the mandible grew significantly during fixed functional appliance treatment combined with GH therapy, with stable results during 2 years 11 months of retention. More studies are needed to evaluate GH therapy as a supplement in Class II treatment.
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Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model
ABSTRACTObjectives:. To investigate the individual and synergistic effects of growth hormone (GH) and functional appliance (FA) on mandibular growth in an adolescent rat model.Materials and Methods:. Forty adolescent (6-week-old) female Wistar rats were randomly divided into four groups (10 rats...
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Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model
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Here we see 1mm increase in mandibular length following GH therapy alone in adolescent rat (22mm vs 23mm). That's a 5% increase. Now let's compare that to a human(me) with an overbite and a jaw length of 16.6cm. 16.6cm + 5% (0.8cm) = 17.4cm(!) (Normal sized mandible should have a length within or above 17.22–19.33 cm in males) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591016/] The average BSSO will bring your jaw forward on average 0.6cm (that's a 4% increase) and anything above that you increase the risk of complications.
Now my theory on how to fix overbite nonsurgically in an adult class II case.
Alright. Since GH grows your jaw and potentially all of your craniofacial region even after you have finished your growth
you could theoretically treat a class ii patient with GH therapy and a headgear, inorder to prevent your maxilla growing forwards and letting the lower jaw come forward and catch up in growth, which will in effect bring your jaws to a class I occlusion.
tl;dr GH brings equal or higher increase in mandibular length compared to BSSO but GH therapy in orthodontics is still in experimental stage.
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