High iq only: are osteoclasts "bad"?

[stress]

I'm currently doing some research on this but I thought to get some opinions on here in the meantime.

My question is, would inhibiting osteoclasts be a net positive? or negative, in terms of facial aesthetic benefits. We know that by stopping osteoclasts from resorbing bone we can increase bone density, but is that necessarily a good thing for improving your appearance? How much benefit could we expect to gain from bone remodeling during late puberty/after, vs bone strengthening.

Could anyone link me some good articles about craniofacial remodeling at a late age. Outside of orthotropics/myo which is very theoretical I don't know much about how the bones typically remodel.

 

[bddcoper]

ask chatgpt

 

[Moosemilk56]

I'm currently doing some research on this but I thought to get some opinions on here in the meantime.

My question is, would inhibiting osteoclasts be a net positive? or negative, in terms of facial aesthetic benefits. We know that by stopping osteoclasts from resorbing bone we can increase bone density, but is that necessarily a good thing for improving your appearance? How much benefit could we expect to gain from bone remodeling during late puberty/after, vs bone strengthening.

Could anyone link me some good articles about craniofacial remodeling at a late age. Outside of orthotropics/myo which is very theoretical I don't know much about how the bones typically remodel.

why would you want to inhibit ideally you would want to upregulate both clasts and blasts could see if you would want to upregulate blasts only but would this not also upregulate clasts also theyre synergisitic I believe

 

[stress]

why would you want to inhibit ideally you would want to upregulate both clasts and blasts could see if you would want to upregulate blasts only but would this not also upregulate clasts also theyre synergisitic I believe

The only known osteoporosis drug class that does not cause long term suppression/dependency is bisphosphonates. They work by inhibiting the effects of osteoclasts in the bone. I was doing some research and I might make a thread as to why these actually create a bad environment for facial aesthetics.

 

[Moosemilk56]

The only known osteoporosis drug class that does not cause long term suppression/dependency is bisphosphonates. They work by inhibiting the effects of osteoclasts in the bone. I was doing some research and I might make a thread as to why these actually create a bad environment for facial aesthetics.

interested in seeing the thread