Male-typical Brain features were associated with greater cognitive abilities in both girls and boys.

[jailcel]

Sex impacts the development of the brain and cognition differently across individuals. However, the literature on brain sex dimorphism in humans is mixed. We aim to investigate the biological underpinnings of the individual variability of sexual dimorphism in the brain and its impact on cognitive performance. To this end, we tested whether the individual difference in brain sex would be linked to that in cognitive performance that is influenced by genetic factors in prepubertal children (N = 9,658, ages 9–10 years old; the Adolescent Brain Cognitive Development study). To capture the interindividual variability of the brain, we estimated the probability of being male or female based on the brain morphometry and connectivity features using machine learning (herein called a brain sex score). The models accurately classified the biological sex with a test ROC–AUC of 93.32%.

As a result, a greater brain sex score correlated significantly with greater intelligence (pfdr < .001, = .011–.034; adjusted for covariates) and higher cognitive genome-wide polygenic scores (GPSs) (pfdr < .001,  < .005). Structural equation models revealed that the GPS-intelligence association was significantly modulated by the brain sex score, such that a brain with a higher maleness score (or a lower femaleness score) mediated a positive GPS effect on intelligence (indirect effects = .006–.009; p = .002–.022; sex-stratified analysis). The finding of the sex modulatory effect on the gene–brain–cognition relationship presents a likely biological pathway to the individual and sex differences in the brain and cognitive performance in preadolescence.

https://onlinelibrary.wiley.com/doi/10.1002/hbm.25888

 

[jailcel]

bump ts, need more discussion on the sexpill

 

[Outlander]

0

 

[Giorgio]

no cognitive abilities for your looks & social status buddy

 

[jailcel]

no cognitive abilities for your looks & social status buddy

are you fucking kidding me?

 

[Giorgio]

are you fucking kidding me?

slightly

 

[mohito]

This whole text is more about sex related brain organization shaping genetic expression than "male vs. female brains".
Brain actually converts test into estrogen via aromatase. Many neural effects traditionally attributed to "male" hormones are actually estrogen mediated

 

[jailcel]

slightly

ofcourse i make a post relating to cognitive function based upon sex (0 relation to lookism) and it ties back into looks somehow. fmtcl

 

[jailcel]

This whole text is more about sex related brain organization shaping genetic expression than "male vs. female brains".
Brain actually converts test into estrogen via aromatase. Many neural effects traditionally attributed to "male" hormones are actually estrogen mediated

its about individual differences in sex related brain organization which influence how cognitive genes are expressed

 

[mohito]

its about individual differences in sex related brain organization which influence how cognitive genes are expressed

The paper is about individual variation and overlap. The brain sex score is continuum of mixed features and my point was that some of sex related brain effects are actually estrogen driven

 

[jailcel]

The paper is about individual variation and overlap. The brain sex score is continuum of mixed features and my point was that some of sex related brain effects are actually estrogen driven

correct, my bad if the past posts were unclear.