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This is kinda informal because I don't have much time hence the name (research dump). I'm basically doing as much research as I can because I'm about to wageslave as a security guard for 40 hours a week. Just understand the green text is me talking
What it is?:Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine. In plasma the level of GHK is about 200 ng/mL (10−7 M) at age 20, but declines to 80 ng/mL by age 60.
I'm going to list the sources that I found about this substance and just list some key findings for lazycels. I copy and pasted everything tbh
Up-to-date, it is established that GHK-Cu is able to:
Studies showing the importance in collogenmaxxing (3 Seperate studies)
Study 1:A number of clinical studies confirmed GHK-Cu’s ability to improve appearance of aging skin. A facial cream containing GHK-Cu applied for 12 weeks to the facial skin of 71 women with mild to advanced signs of photoaging increased skin density and thickness, reduced laxity, improved clarity, reduced fine lines and the depth of wrinkles [14].
Study 2:A GHK-Cu eye cream applied for 12 weeks to around-the-eye area of 41 women with mild to advanced photodamage performed better than placebo and vitamin K cream. It reduced lines and wrinkles, improved overall appearance, and increased skin density and thickness [15].
Study 3:-Cu applied to thigh skin for 12 weeks improved collagen production in 70% of the women treated, in contrast to 50% treated with the vitamin C cream, and 40% treated with retinoic acid [16]. In addition to improving skin laxity, clarity, firmness and appearance, reducing fine lines, coarse wrinkles and mottled pigmentation, and increasing skin density and thickness, GHK-Cu cream applied twice daily for 12 weeks also strongly stimulated dermal keratinocyte proliferation [17].
With their pilot study for topical application of copper tripeptide complexes in aged skin, Krüger et al. confirmed an increase in skin thickness in the range of the epidermis and dermis, improved skin hydration, a significant smoothing of the skin by stimulating collagen synthesis, increased skin elasticity, a significant improvement in skin contrast and an increased production of collagen I [18,19].
Study showing importance in hair growth(I can't seem to find any clinical studies of of ghk-cu's affects on hair growth but I have found studies on other types of copper peptides)
Study 1:“A copper binding peptide (PC1031) had the effect of follicular enlargement on the back skin of fuzzy rats, covering the vellus follicles; the effect was similar to that of topical minoxidil.”
Source:https://www.ncbi.nlm.nih.gov/pubmed/8326148
Study 2:This trial tested the effects of AHK-Cu, a copper peptide closely related to GHK-Cu, on human hair follicles and found that:
The dermal papilla is what regulates the development and growth of hair follicles. When mature, it instructs surrounding cells to proliferate and differentiate to create hair. If copper peptides result in more dermal papilla cells, as suggested by this study, then it seems likely they may encourage hair growth too. In fact, multiplying dermal papilla cells is one of the proposed methods for hair cloning.
We can assume GHK-CU will have a similar effect on hair growth
Although I could not actually find any studies on it multiple of the sources I've found stated that copper petides can block dht.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/#B14-ijms-19-01987
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
https://gro.md/blogs/blog/5-ways-copper-peptides-boost-hair-growth
https://huskybeard.com/blogs/better-beard-blog/copper-peptides-for-beard-growth
I might personally use this for collagenmaxxing and hair loss prevention. If you like this please let me know when to tag you in the next "Research dump" where I'll just dump everything I learned in my looksmaxxing research
Here's who I think can benefit from this. Mainly picking out baldcels,oldcels ,aspie scientist and roiders
@Ritalincel @AspiringChad @Insomniac @fobos @CupOfCoffee @Vanillestorms @Mr_Norwood @Enigmatic93 @jefferson @Intel.Imperitive @ZUZZCEL
@mojopin @OCDMaxxing @Tony @x30001 @Pex1992 @Extra Chromosome @Soulsmaxx
What it is?:Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine. In plasma the level of GHK is about 200 ng/mL (10−7 M) at age 20, but declines to 80 ng/mL by age 60.
I'm going to list the sources that I found about this substance and just list some key findings for lazycels. I copy and pasted everything tbh
Up-to-date, it is established that GHK-Cu is able to:
- -
Tighten loose skin and reverse thinning of aged skin - -
Repair protective skin barrier proteins - -
Improve skin firmness, elasticity, and clarity - -
Reduce fine lines, depth of wrinkles, and improve structure of aged skin - -
Smooth rough skin - -
Reduce photodamage, mottled hyperpigmentation, skin spots and lesions - -
Improve overall skin appearance - -
Stimulate wound healing - -
Protect skin cells from UV radiation - -
Reduce inflammation and free radical damage - -
Increase hair growth and thickness, enlarge hair follicle size
Studies showing the importance in collogenmaxxing (3 Seperate studies)
Study 1:A number of clinical studies confirmed GHK-Cu’s ability to improve appearance of aging skin. A facial cream containing GHK-Cu applied for 12 weeks to the facial skin of 71 women with mild to advanced signs of photoaging increased skin density and thickness, reduced laxity, improved clarity, reduced fine lines and the depth of wrinkles [14].
Study 2:A GHK-Cu eye cream applied for 12 weeks to around-the-eye area of 41 women with mild to advanced photodamage performed better than placebo and vitamin K cream. It reduced lines and wrinkles, improved overall appearance, and increased skin density and thickness [15].
Study 3:-Cu applied to thigh skin for 12 weeks improved collagen production in 70% of the women treated, in contrast to 50% treated with the vitamin C cream, and 40% treated with retinoic acid [16]. In addition to improving skin laxity, clarity, firmness and appearance, reducing fine lines, coarse wrinkles and mottled pigmentation, and increasing skin density and thickness, GHK-Cu cream applied twice daily for 12 weeks also strongly stimulated dermal keratinocyte proliferation [17].
With their pilot study for topical application of copper tripeptide complexes in aged skin, Krüger et al. confirmed an increase in skin thickness in the range of the epidermis and dermis, improved skin hydration, a significant smoothing of the skin by stimulating collagen synthesis, increased skin elasticity, a significant improvement in skin contrast and an increased production of collagen I [18,19].
Study showing importance in hair growth(I can't seem to find any clinical studies of of ghk-cu's affects on hair growth but I have found studies on other types of copper peptides)
Study 1:“A copper binding peptide (PC1031) had the effect of follicular enlargement on the back skin of fuzzy rats, covering the vellus follicles; the effect was similar to that of topical minoxidil.”
Source:https://www.ncbi.nlm.nih.gov/pubmed/8326148
Study 2:This trial tested the effects of AHK-Cu, a copper peptide closely related to GHK-Cu, on human hair follicles and found that:
Study 3: This study also shows how copper peptides have been proven to increase hair transplant success“AHK-Cu (10(-12) – 10(-9) M) stimulated the elongation of human hair follicles ex vivo and the proliferation of [dermal papilla cells] in vitro […] The present study proposed that AHK-Cu promotes the growth of human hair follicles, and this stimulatory effect may occur due to stimulation of the proliferation and the preclusion of the apoptosis of [dermal papilla cells].”
The dermal papilla is what regulates the development and growth of hair follicles. When mature, it instructs surrounding cells to proliferate and differentiate to create hair. If copper peptides result in more dermal papilla cells, as suggested by this study, then it seems likely they may encourage hair growth too. In fact, multiplying dermal papilla cells is one of the proposed methods for hair cloning.
We can assume GHK-CU will have a similar effect on hair growth
Although I could not actually find any studies on it multiple of the sources I've found stated that copper petides can block dht.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/#B14-ijms-19-01987
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
https://gro.md/blogs/blog/5-ways-copper-peptides-boost-hair-growth
https://huskybeard.com/blogs/better-beard-blog/copper-peptides-for-beard-growth
I might personally use this for collagenmaxxing and hair loss prevention. If you like this please let me know when to tag you in the next "Research dump" where I'll just dump everything I learned in my looksmaxxing research
Here's who I think can benefit from this. Mainly picking out baldcels,oldcels ,aspie scientist and roiders
@Ritalincel @AspiringChad @Insomniac @fobos @CupOfCoffee @Vanillestorms @Mr_Norwood @Enigmatic93 @jefferson @Intel.Imperitive @ZUZZCEL
@mojopin @OCDMaxxing @Tony @x30001 @Pex1992 @Extra Chromosome @Soulsmaxx