revisiting Tren and synthetic androgens in general

Sachlichkeit

Sachlichkeit

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19nor 7b tren TRENBOLONE causes brain damage by accumulating in the hippocampal regions of the brain (in animal studies) DIRECTLY caused neural apoptosis (death of neurons) and was mediated by estrogen and testosterone (meaning the damage was carried out partially by E & T). We know estrogen is neuroprotective, not commonly mentioned is that testosterone is as well. Tren also interfered with Testosterone's neuroprotective effects.

Trens CNS central nervous system (the brain and the spine's) neurotoxicity was known and even better there are known ways to mitigate it, as for hippocampal accumulation, not so much. A longterm or high dose will most likely cause some sort of brain damage, effecting cognition and memory.

People run tren for a couple reasons. lower required protein intake for muscle growth, extreme anti catabolism (keeping muscle in a cut,) 4-5x the stronger androgen binding affinity than testosterone, less downstreams for androgens to spill out of, and longer occupation and the androgen receptor, enhanced IGF1 satellite cell responsiveness meaning it almost certainly contributes to the new and permanent creation of muscle fibers thereby permanently increasing your capacity for muscle, and bar none the best androgen for IGF1 expression upregulation. Bone growth from GH on tren is enhanced.

Tren upregulates adrenergic tone, potentially putting the user in a constant state of fight or flight. It negatively modulates the prefrontal cortex thus reducing impulse control by disregulating dopamine while simultaneously increasing prolactin, effecting libido, motivation, and giving you gynecomastia (man tits.)

so ur looking at less control, impaired judgement, less control of emotion, paranoia (anecdotal use of tren paranoia is common.) blablabla

also because of androgen binding affinity, hairloss. 5ars dutasteride and finasteride will not work.

19nors nandrolone and tren damage the fertility axis where as standard exogenous testosterone does not. don't ask me how, I wrote a thread on it and forgot.

HCG covers the sperm count, HMG covers DNA "completeness" and sperm morphology. If you are using 19nors you should be using HMG, if your woman has a miscarriage it might be your fault as your sperm has 2 heads, incomplete dna, etcetera because you only supplemented half of the hypogonadal pituitary axis.

What would a tren ancillary stack look like?

HCG & HMG
Cabergoline for prolactin (though as far as I can tell doesn't do anything for dopamine disregulation,)
High dose melatonin +100mg for sleep and as anti-oxidant to combat oxidative stress
intramuscular cerebrolysin to slow brain damage
intranasal insulin also for brain damage

this is on top of the standard steroid stack, which is typically blood pressure, hair, cholesterol, skin, cardiac remodeling, liver support, and so on and so forth

nandrolone is the weaker 19nor steroid but still hits the fertility axis and doesn't appear to be neuroprotective. It was initially discussed for bones as it stimulates osteoblast proliferation milligram per milligram STRONGER than test and has some interesting properties that make it good for people with back and joint issues, but like the people who developed it 30 years ago or however long, I am scrapping it

So heres the deal. There is really only 1 "good steroid' and that is testosterone

what about orals, x and y? test or nothing boys
 

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if test didnt bloat it'd fs be the best steroid to ever exist but ill take my brain getting fried so i can be a lil bit leaner with tren
 
if test didnt bloat it'd fs be the best steroid to ever exist but ill take my brain getting fried so i can be a lil bit leaner with tren
eplerenone and e2 control
 
Today has been a day of reading bad things about trenbolone man, and shit seems to fuck you up hard even at low doses.
 
K

19nor 7b tren TRENBOLONE causes brain damage by accumulating in the hippocampal regions of the brain (in animal studies) DIRECTLY caused neural apoptosis (death of neurons) and was mediated by estrogen and testosterone (meaning the damage was carried out partially by E & T). We know estrogen is neuroprotective, not commonly mentioned is that testosterone is as well. Tren also interfered with Testosterone's neuroprotective effects.

Trens CNS central nervous system (the brain and the spine's) neurotoxicity was known and even better there are known ways to mitigate it, as for hippocampal accumulation, not so much. A longterm or high dose will most likely cause some sort of brain damage, effecting cognition and memory.

People run tren for a couple reasons. lower required protein intake for muscle growth, extreme anti catabolism (keeping muscle in a cut,) 4-5x the stronger androgen binding affinity than testosterone, less downstreams for androgens to spill out of, and longer occupation and the androgen receptor, enhanced IGF1 satellite cell responsiveness meaning it almost certainly contributes to the new and permanent creation of muscle fibers thereby permanently increasing your capacity for muscle, and bar none the best androgen for IGF1 expression upregulation. Bone growth from GH on tren is enhanced.

Tren upregulates adrenergic tone, potentially putting the user in a constant state of fight or flight. It negatively modulates the prefrontal cortex thus reducing impulse control by disregulating dopamine while simultaneously increasing prolactin, effecting libido, motivation, and giving you gynecomastia (man tits.)

so ur looking at less control, impaired judgement, less control of emotion, paranoia (anecdotal use of tren paranoia is common.) blablabla

also because of androgen binding affinity, hairloss. 5ars dutasteride and finasteride will not work.

19nors nandrolone and tren damage the fertility axis where as standard exogenous testosterone does not. don't ask me how, I wrote a thread on it and forgot.

HCG covers the sperm count, HMG covers DNA "completeness" and sperm morphology. If you are using 19nors you should be using HMG, if your woman has a miscarriage it might be your fault as your sperm has 2 heads, incomplete dna, etcetera because you only supplemented half of the hypogonadal pituitary axis.

What would a tren ancillary stack look like?

HCG & HMG
Cabergoline for prolactin (though as far as I can tell doesn't do anything for dopamine disregulation,)
High dose melatonin +100mg for sleep and as anti-oxidant to combat oxidative stress
intramuscular cerebrolysin to slow brain damage
intranasal insulin also for brain damage

this is on top of the standard steroid stack, which is typically blood pressure, hair, cholesterol, skin, cardiac remodeling, liver support, and so on and so forth

nandrolone is the weaker 19nor steroid but still hits the fertility axis and doesn't appear to be neuroprotective. It was initially discussed for bones as it stimulates osteoblast proliferation milligram per milligram STRONGER than test and has some interesting properties that make it good for people with back and joint issues, but like the people who developed it 30 years ago or however long, I am scrapping it

So heres the deal. There is really only 1 "good steroid' and that is testosterone

what about orals, x and y? test or nothing boys
Great post. You clearly put time and effort into writing this formally and scientifically.

It seems that estrogen should keep your neurons protected as long as you maintain balance and prevent it from dropping too low.
 
K

19nor 7b tren TRENBOLONE causes brain damage by accumulating in the hippocampal regions of the brain (in animal studies) DIRECTLY caused neural apoptosis (death of neurons) and was mediated by estrogen and testosterone (meaning the damage was carried out partially by E & T). We know estrogen is neuroprotective, not commonly mentioned is that testosterone is as well. Tren also interfered with Testosterone's neuroprotective effects.

Trens CNS central nervous system (the brain and the spine's) neurotoxicity was known and even better there are known ways to mitigate it, as for hippocampal accumulation, not so much. A longterm or high dose will most likely cause some sort of brain damage, effecting cognition and memory.

People run tren for a couple reasons. lower required protein intake for muscle growth, extreme anti catabolism (keeping muscle in a cut,) 4-5x the stronger androgen binding affinity than testosterone, less downstreams for androgens to spill out of, and longer occupation and the androgen receptor, enhanced IGF1 satellite cell responsiveness meaning it almost certainly contributes to the new and permanent creation of muscle fibers thereby permanently increasing your capacity for muscle, and bar none the best androgen for IGF1 expression upregulation. Bone growth from GH on tren is enhanced.

Tren upregulates adrenergic tone, potentially putting the user in a constant state of fight or flight. It negatively modulates the prefrontal cortex thus reducing impulse control by disregulating dopamine while simultaneously increasing prolactin, effecting libido, motivation, and giving you gynecomastia (man tits.)

so ur looking at less control, impaired judgement, less control of emotion, paranoia (anecdotal use of tren paranoia is common.) blablabla

also because of androgen binding affinity, hairloss. 5ars dutasteride and finasteride will not work.

19nors nandrolone and tren damage the fertility axis where as standard exogenous testosterone does not. don't ask me how, I wrote a thread on it and forgot.

HCG covers the sperm count, HMG covers DNA "completeness" and sperm morphology. If you are using 19nors you should be using HMG, if your woman has a miscarriage it might be your fault as your sperm has 2 heads, incomplete dna, etcetera because you only supplemented half of the hypogonadal pituitary axis.

What would a tren ancillary stack look like?

HCG & HMG
Cabergoline for prolactin (though as far as I can tell doesn't do anything for dopamine disregulation,)
High dose melatonin +100mg for sleep and as anti-oxidant to combat oxidative stress
intramuscular cerebrolysin to slow brain damage
intranasal insulin also for brain damage

this is on top of the standard steroid stack, which is typically blood pressure, hair, cholesterol, skin, cardiac remodeling, liver support, and so on and so forth

nandrolone is the weaker 19nor steroid but still hits the fertility axis and doesn't appear to be neuroprotective. It was initially discussed for bones as it stimulates osteoblast proliferation milligram per milligram STRONGER than test and has some interesting properties that make it good for people with back and joint issues, but like the people who developed it 30 years ago or however long, I am scrapping it

So heres the deal. There is really only 1 "good steroid' and that is testosterone

what about orals, x and y? test or nothing boys
I forgot 2 post the abstract
 
eplerenone and e2 control
eplerenone doesnt seem to make a big difference in my face, and using ai to lower e2 is tricky since estrogen is neuroprotective + other benefits and defeats the purpose of using test in the first place imo
 
eplerenone doesnt seem to make a big difference in my face, and using ai to lower e2 is tricky since estrogen is neuroprotective + other benefits and defeats the purpose of using test in the first place imo
brain damage or moonface anon call it
 
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