The truth about Minoxidil - The holy grail or overhyped Looksmin?

[slaters]

been on oral minox 2.5 mg for 2 months zero bloat

How’s the results so far

 

[takethezincpill]

Thanks

 

[renn]

How’s the results so far

amazing eyelashes and eyebrows are moggin

 

[asianslayer]

Back again on this thread. I am a shortface with a recessed maxilla so even at sub10% bf my face will remain bloated, no angularity. so ill be taking minox permanently so id have mogger lashes instead. Im asian so longer lashes would nichemaxx me since asians in general do not have long lashes especially lashes on the lower eyelid

 

[rom]

Maybe i'm just coping cuz i'm 3 weeks deep on using it, but wouldn't de-bloating measures counter the minox effect, like drinking more water or potassium? Even if it reduced to like half bloat, minoxidil is still a huge boost that most people have benefitted from.

still really good thread tho

 

[jeff1234]

Heh, atleast I have long eyelashes

View attachment 3682486

@Jonasㅤㅤ⠀ hey man, what about minoxidil effect on lysyl hydroxylase? i didnt see you talked about it or maybe i skippped it, its better to pair ghk cu with it (injectable of course) or just suffer until you stop using it?
im already on it and im using ghk cu to prevent inhibation of lysyl hydroxyplase. thoughts?

 

[jeff1234]

@Jonasㅤㅤ⠀ hey man, what about minoxidil effect on lysyl hydroxylase? i didnt see you talked about it or maybe i skippped it, its better to pair ghk cu with it (injectable of course) or just suffer until you stop using it?
im already on it and im using ghk cu to prevent inhibation of lysyl hydroxyplase. thoughts?

@Jonasㅤㅤ⠀ i would apreciatte if you could not ignore me.

 

[Jonasㅤㅤ]

It definitely depends on dose i feel 2.5mg daily will have very minor retention if any

been on oral minox 2.5 mg for 2 months zero bloat

Bloating is a gradual process, you think you can notice gradual changes that easily?

Everyone including me bloats on oral min. @chadbeingmade @´´´´´´´´ @imontheloose

Have much fun waking up like this every day.

I am a shortface with a recessed maxilla so even at sub10% bf my face will remain bloated, no angularity. so ill be taking minox permanently so id have mogger lashes instead.

It is bad, so just make it fucking worse theory. No amount of eyelashes can compensate for extreme bloating.

wouldn't de-bloating measures counter the minox effect, like drinking more water or potassium?

Imagine minoxidil like some molecule that bypasses all fundamental laws of physics.

You would need to constantly overdose on multiple diuretics to potentially get rid of the water retention.

JFL at "drinking more water or potassium" BTW.

what about minoxidil effect on lysyl hydroxylase?

What a fancy way to say it affects the collagen synthesis.

maybe i skippped it

Low social IQ. JFL at asking about a topic and proceeding to say you didn't even read the text.

its better to pair ghk cu with it (injectable of course)

"Yo fellow smokers, can I get a cigarette? Marlboro red of course. "


@Eltrē

or just suffer until you stop using it?

What do you expect me to reply?

Caging at the fact you tried your best to sound smart, but then proceeded to ask the most retarded question.

In other words: "Minox affects collagen, should I take something that improves collagen?"

@Jonasㅤㅤ⠀ i would apreciatte if you could not ignore me.

 

[imontheloose]

Bloating is a gradual process, you think you can notice gradual changes that easily?

Everyone including me bloats on oral min. @

@chadbeingmade @

@´´´´´´´´ @

@imontheloose

Have much fun waking up like this every day.

I noticed bloating within a couple weeks, honestly.

 

[jeff1234]

Bloating is a gradual process, you think you can notice gradual changes that easily?

Everyone including me bloats on oral min. @chadbeingmade @´´´´´´´´ @imontheloose

Have much fun waking up like this every day.
View attachment 3844773

It is bad, so just make it fucking worse theory. No amount of eyelashes can compensate for extreme bloating.

Imagine minoxidil like some molecule that bypasses all fundamental laws of physics.

You would need to constantly overdose on multiple diuretics to potentially get rid of the water retention.

JFL at "drinking more water or potassium" BTW.

What a fancy way to say it affects the collagen synthesis.

Low social IQ. JFL at asking about a topic and proceeding to say you didn't even read the text.

"Yo fellow smokers, can I get a cigarette? Marlboro red of course. "
View attachment 3844796

@Eltrē

What do you expect me to reply?

Caging at the fact you tried your best to sound smart, but then proceeded to ask the most retarded question.

In other words: "Minox affects collagen, should I take something that improves collagen?"

View attachment 3844817

just wanted to know if ghk cu is a good anchillary for that.
and i didnt skipped the thread, i read everything (great thread), i just meant maybe i missed the part where you talked about it.
and why are you so mad? cant even ask questions smh.

 

[slaters]

just wanted to know if ghk cu is a good anchillary for that.
and i didnt skipped the thread, i read everything (great thread), i just meant maybe i missed the part where you talked about it.
and why are you so mad? cant even ask questions smh.

I mean bro ..

In other words: "Minox affects collagen, should I take something that improves collagen

 

[jeff1234]

I mean bro ..

i wanted to ask which ones to take tho. what is the best to combat the collagen suppression.

 

[slaters]

i wanted to ask which ones to take tho. what is the best to combat the collagen suppression.

Ghk and vitamin c would be your best bet and moisturizer

 

[ikramy]

Spironolactone

Thought it blocks AR receptors too?

 

[stormspirit]

mogger eyelashes

God I hate this forum, there was time when I considered bonesmashing as something legit , eyelashes doesnt do shit in male aesthetics, and people who try to apply minox on their eyes gonna lose vision

 

[renn]

Bloating is a gradual process, you think you can notice gradual changes that easily?

Everyone including me bloats on oral min. @chadbeingmade @´´´´´´´´ @imontheloose

Have much fun waking up like this every day.
View attachment 3844773

It is bad, so just make it fucking worse theory. No amount of eyelashes can compensate for extreme bloating.

Imagine minoxidil like some molecule that bypasses all fundamental laws of physics.

You would need to constantly overdose on multiple diuretics to potentially get rid of the water retention.

JFL at "drinking more water or potassium" BTW.

What a fancy way to say it affects the collagen synthesis.

Low social IQ. JFL at asking about a topic and proceeding to say you didn't even read the text.

"Yo fellow smokers, can I get a cigarette? Marlboro red of course. "
View attachment 3844796

@Eltrē

What do you expect me to reply?

Caging at the fact you tried your best to sound smart, but then proceeded to ask the most retarded question.

In other words: "Minox affects collagen, should I take something that improves collagen?"

View attachment 3844817

i just hopped off oral minox was giving me heart issues plus i realized it did actually bloat me abit im switchin to topical eyebrows only

 

[Axhar1]

so I js apply topical on brows and hope brows + lashes grow?

 

[JamesHairyBalls]

thank you god for giving me thick Mediterranean eyebrows and eyelashes. only positive traits i have

Lowiq

 

[JamesHairyBalls]

so I js apply topical on brows and hope brows + lashes grow?

Grey

 

[CopeTilliRope]

Bloating is a gradual process, you think you can notice gradual changes that easily?

Everyone including me bloats on oral min. @chadbeingmade @´´´´´´´´ @imontheloose

Have much fun waking up like this every day.
View attachment 3844773

It is bad, so just make it fucking worse theory. No amount of eyelashes can compensate for extreme bloating.

Imagine minoxidil like some molecule that bypasses all fundamental laws of physics.

You would need to constantly overdose on multiple diuretics to potentially get rid of the water retention.

JFL at "drinking more water or potassium" BTW.

What a fancy way to say it affects the collagen synthesis.

Low social IQ. JFL at asking about a topic and proceeding to say you didn't even read the text.

"Yo fellow smokers, can I get a cigarette? Marlboro red of course. "
View attachment 3844796

@Eltrē

What do you expect me to reply?

Caging at the fact you tried your best to sound smart, but then proceeded to ask the most retarded question.

In other words: "Minox affects collagen, should I take something that improves collagen?"

minox is the devil but weirdly i had zeroo facial bloating on om 6 mg and i get moonface on topical maybe it's a vehicle allergy issue

 

[jackisbped]

high iq

 

[duromaxxing]

God I hate this forum, there was time when I considered bonesmashing as something legit , eyelashes doesnt do shit in male aesthetics, and people who try to apply minox on their eyes gonna lose vision

“eyelashes doesn’t do shit in male aesthetics” jfl

 

[Tatarslayerr]

“eyelashes doesn’t do shit in male aesthetics” jfl

Noah R

 

[johnjohnson96]

only about 10% of oral min users get peripheral edema/bloating though so

I thought it was much higher than that I'm probably wrong but where did you get that from

 

[e1_xz]

thank you god for giving me thick Mediterranean eyebrows and eyelashes. only positive traits i have

real bruh, the only thing keeping me mtn is my mediterranean phenotype

 

[stormspirit]

“eyelashes doesn’t do shit in male aesthetics” jfl

How the fuck you gonna apply minox on eyelids without damaging your eyes , retard?
Do you want this look? Go for it

 

[Jonasㅤㅤ]

Thought it blocks AR receptors too?

That's why I only recommend eplerenone to manage aldosterone.

God I hate this forum, there was time when I considered bonesmashing as something legit , eyelashes doesnt do shit in male aesthetics, and people who try to apply minox on their eyes gonna lose vision

Don't visit this forum in that case. Eyelashes add a beautiful contrast to any eye area, hide UEE, are just natural and a health indicator meaning being off in this regard will just look off, obviously. Eyelashes are important.

Just take a look at this eye area.

i just hopped off oral minox was giving me heart issues plus i realized it did actually bloat me abit im switchin to topical eyebrows only

You saved your life.

How the fuck you gonna apply minox on eyelids without damaging your eyes , retard?
Do you want this look? Go for it
View attachment 3981941

Just use an ugly individual using make-up and fake lashes to prove your point that eyelashes aren't aesthetic theorem. Smartest org user.

 

[ikramy]

That's why I only recommend eplerenone to manage aldosterone.

Don't visit this forum in that case. Eyelashes add a beautiful contrast to any eye area, hide UEE, are just natural and a health indicator meaning being off in this regard will just look off, obviously. Eyelashes are important.

Just take a look at this eye area.

View attachment 3985510

You saved your life.

Just use an ugly individual using make-up and fake lashes to prove your point that eyelashes aren't aesthetic theorem. Smartest org user.

Damn the safest drug you have on your bio is test ironically, you’re doing a Russian roulette with your organs atp.

 

[duromaxxing]

How the fuck you gonna apply minox on eyelids without damaging your eyes , retard?
Do you want this look? Go for it
View attachment 3981941

your obviously retarded, your not supposed to apply it on ur fucking eyelids, and u will never look like that of minoxidil fucking dumbass

 

[Iblameginger]

will rubbing a little bit of minoxidil on your cheeks and eyebrows rlly cause this much bloating?

 

[laworg]

View attachment 3682319
The truth about Minoxidil - Part 1​

Spoiler: Previous Part

The truth about ... - The new thread series, AMA

The truth about ... - Part 0 This thread series will cover compounds/concepts that are discussed daily on here. It's a crossover between @chadisbeingmade and me. Potentially other users too, lmk. The purpose is to shed light on the reality behind these compounds/concepts. The first...

looksmax.org

Growing your eyelashes and eyebrows is one of the best and only true softmaxxes.

Because of that, many people choose compounds like Minoxidil to grow hairs in their eye area or even on the scalp.

View attachment 3682324View attachment 3682326
​

This thread will reveal why you should be cautious with Minoxidil - And how it could actually harm your looks.

---

History

Spoiler: History

Minoxidil was developed for antihypertensive and vasodilative purposes.

View attachment 3682339

Though this use case was later dropped as even the developing scientists figured out that it isn't efficient at what it does.

It's the last resort when it comes to hypertension - Only being used when two agents and/or a diuretic aren't enough.

Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension - PMC

Minoxidil is a direct vasodilator introduced in the early 1970s for the treatment of hypertension. It is capable of reducing blood pressure in most persons with resistant hypertension where therapy has failed with multidrug regimens. Minoxidil's ...

pmc.ncbi.nlm.nih.gov

And not even monotherapy is a valid option. It has to be combined with a loop diuretic either way because of the sodium and potassium retention it causes.

Appeal in PSL-Spaces

Spoiler: Appeal in PSL-Spaces

The other use case beside hypertension is hair growth.

Unfortunately it's not the best option for stopping scalp hair loss as that is a mainly AR-mediated pathway.

That means it won't prevent any miniaturization of the hair follicle, @chadisbeingmade is going to make a thread covering the topic of 5ARIs.

The other use case is like I mentioned previously, growing the hairs in your eye area.

View attachment 3682266

It's an exaggerated example removing the hair completely obviously, but I hope you can see how important they are.

There are two ways you can grow them via Minoxidil: Topical and Oral.

Topical

Spoiler: Topical

Topical Minoxidil is pretty harsh on your eyes, that's why you should only apply it on your eyebrows.

Another thing is that Minoxidil can cause fat loss in your upper eyelid as Minoxidil stimulates factors like PGE2 (The active ingredient in Latisse).

HMGB1 promotes hair growth via the modulation of prostaglandin metabolism - PMC

Unexpected hair growth can occur after tissue injury. The pathogenic mechanism for this phenomenon is unknown but is likely related to inflammatory mediators. One such mediator is high-mobility group box 1 (HMGB1), a ubiquitous nuclear protein that ...

pmc.ncbi.nlm.nih.gov

Oral

Spoiler: Oral

Oral Minoxidil is very effective in growing your eyelashes, but more of that in the biology section.

[Brutal UEE right there, just look at the lashes duh ]
View attachment 3682288

Biology

Spoiler: Biology

The unfortunate truth is, if you are using Minoxidil you are going to retain a ton more water and be bloated.

This is primarely mediated by the activation of the Renin-Angiotensin-Aldosterone-System.

View attachment 3682292

I'll try to keep it short:

1. Minoxidil vasodilates blood vessels
2. Activation of RAAS
3. Aldosterone increase
4. Sodium, potassium and water retention

In short, this means your Aldosterone skyrockets making you retain a ton more sodium/potassium and consequently more water.

This means it's a big trade off, hair growth or bloat. What do you choose, no water retention or mogger eyelashes?

View attachment 3682392

Conclusion

Spoiler: Conclusion

The only possible solution to solve the bloat is using an aldosterone-antagonist.

View attachment 3682299

In theory using an aldosterone-antagonist like Eplerenone or Spironolactone should work, but even then there is quite some anecdotal evidence that this doesn't work.



TL;DR: There are only two viable options now:

• Topical Minoxidil on eyebrows, which also affects your lashes.
• Oral Minoxidil only in combination with an aldosterone-antagonist.

---

I hope you learned something new today.

Feel free to AMA.

Spoiler: Tags

@halloweed @menas @Zagro @Drugsmaxxer

What ab something on ur lashes since my upper lashes are decent but my lower ones are shite

 

[Djimo]

will rubbing a little bit of minoxidil on your cheeks and eyebrows rlly cause this much bloating?

i cant bro

 

[hahxdadvx]

is it you?

 

[barambo]

@Jonasㅤㅤ technically... does this mean that i can bloat my reccesed undereye area and larp being projected if i use minox on that specific area?