wtf?? tretinoin actally has a POSITIVE effect on male fertility? or does it have any effect at all

[2d v2]

https://www.researchgate.net/publication/286580047_The_effect_of_systemic_isotretinoin_on_male_fertility

If this is the case idk why the fuck im not hopping right on this stuff.

Imagine pairing it with l-carnitine (has the same effects and also increases androgen receptors)

but then there are studies with the opposite effect(on rats)

Testosterone and progesterone level alterations in the adult rat after retinoid (retinol or retinoic acid) treatment (imprinting) in neonatal or adolescent age - PubMed

Newborn rats were treated with a single dose of vitamin A (retinol), or with three doses of retinoic acid (in the 1st, 3rd and 5th days). Serum testosterone and progesterone level was measured in the four months old male and female rats, respectively. Retinol significantly decreased both hormone...

pubmed.ncbi.nlm.nih.gov

Maybe the effects are veriable and it really has zero effect on fertility/testosterone

Another study showing positive testosterone effects

https://www.sciencedirect.com/science/article/abs/pii/S0006291X89800610

Effect of retinol and retinoic acid on testosterone production by rat Leydig cells in primary culture - PubMed

Adult rat Leydig cells, purified by Percoll density gradient centrifugation, were used to determine the effect of retinol and retinoic acid on steroidogenesis. It was found that both retinoic acid and retinol stimulated testosterone production. Although retinol was less potent than retinoic...

pubmed.ncbi.nlm.nih.gov

There are studies showing a mother shouldnt take it while pregnant, but obviously a fetus in-utero does not need cell/skin turnover. Obvious to why it would harm a fetus.

I wonder if it can somehow modify the sperm structure in some way, there are no real studies. but l-carnitine has good effects on sperm structure, so maybe taking that will offset any potential problems.

It looks like there are no real detriments for a man to take Tretinoin at this point.

 

[StuffedFrog]

the affect would probably be tiny as shit bro what the fuck just use tretinoin

 

[advancevision]

This guy is scared to apply a topical from one obscure study on rats. Wait until he finds out about BPA in plastic and touching receipts.

 

[2d v2]

This guy is scared to apply a topical from one obscure study on rats. Wait until he finds out about BPA in plastic and touching receipts.

What are you talking about, can you read?

the low iq braindead troglodytes of this forum will ever cease to amaze me.

 

[2d v2]

the affect would probably be tiny as shit bro what the fuck just use tretinoin

Do you have a website to buy it?

 

[WhatsMonogamy]

when u put it on your scrotum tell us how it went

 

[2d v2]

when u put it on your scrotum tell us how it went

how about you put it on your asshole and see if it gets rid of your butthole wrinkles

 

[WhatsMonogamy]

how about you put it on your asshole and see if it gets rid of your butthole wrinkles

it was semi humoristic man dont feel attacked. it literally talks about leydig cells in the studys, where do you think those are???

 

[2d v2]

it was semi humoristic man dont feel attacked. it literally talks about leydig cells in the studys, where do you think those are???

yea and it was funny which is why i rated your post as funny

i know what it means, i read the studies. still not putting it on my balls though unless i want a plump bright red flaky ballsack for weeks

 

[Tasty17]

It reduces testosterone.

 

[CyprusGD]

https://www.researchgate.net/publication/286580047_The_effect_of_systemic_isotretinoin_on_male_fertility

If this is the case idk why the fuck im not hopping right on this stuff.

Imagine pairing it with l-carnitine (has the same effects and also increases androgen receptors)

but then there are studies with the opposite effect(on rats)

Testosterone and progesterone level alterations in the adult rat after retinoid (retinol or retinoic acid) treatment (imprinting) in neonatal or adolescent age - PubMed

Newborn rats were treated with a single dose of vitamin A (retinol), or with three doses of retinoic acid (in the 1st, 3rd and 5th days). Serum testosterone and progesterone level was measured in the four months old male and female rats, respectively. Retinol significantly decreased both hormone...

pubmed.ncbi.nlm.nih.gov

Maybe the effects are veriable and it really has zero effect on fertility/testosterone

Another study showing positive testosterone effects

https://www.sciencedirect.com/science/article/abs/pii/S0006291X89800610

Effect of retinol and retinoic acid on testosterone production by rat Leydig cells in primary culture - PubMed

Adult rat Leydig cells, purified by Percoll density gradient centrifugation, were used to determine the effect of retinol and retinoic acid on steroidogenesis. It was found that both retinoic acid and retinol stimulated testosterone production. Although retinol was less potent than retinoic...

pubmed.ncbi.nlm.nih.gov

There are studies showing a mother shouldnt take it while pregnant, but obviously a fetus in-utero does not need cell/skin turnover. Obvious to why it would harm a fetus.

I wonder if it can somehow modify the sperm structure in some way, there are no real studies. but l-carnitine has good effects on sperm structure, so maybe taking that will offset any potential problems.

It looks like there are no real detriments for a man to take Tretinoin at this point.

Isotretinoin is a different story. Topical tretinoin is fine