you should be pinning estrogen (high iq gtfih)

[doidfestroyer]

ok so everyone runs an AI on a height protocol bc estrogen closes plates right, makes sense. but heres the thing estrogen doesnt just bind to one receptor it

binds to ERα and ERβ and they do completely opposite things. ERα in the hypertrophic zone drives closure thats the one youre trying to suppress. but ERβ

in the proliferative zone actually drives chondrocyte proliferation aka the thing that makes you grow. so when u run letrozole ur not selectively blocking

ERα ur just nuking all ur estrogen so both receptors lose signal at the same time. plates close slower yeah but they also grow slower bc u just killed the

signal telling ur chondrocytes to keep dividing. so the actual move is low dose AI to keep ERα quiet then throw in an ERβ selective agonist like s-equol or

liquiritigenin to restore the proliferative signal u just suppressed. stack that with abalo which is already holding chondrocytes in proliferative state via

pthrp and now u got three separate mechanisms all pushing in the same direction. running an AI without addressing ERβ is just leaving the most important

 

[doidfestroyer]

BUMP

 

[doidfestroyer]

bump

 

[foidslayer393]

bump

 

[ANON]

Estrogen helps the liver which converts hgh to igf1 aswell

 

[Planes]

Bump

 

[mewzilla]

ok so everyone runs an AI on a height protocol bc estrogen closes plates right, makes sense. but heres the thing estrogen doesnt just bind to one receptor it

binds to ERα and ERβ and they do completely opposite things. ERα in the hypertrophic zone drives closure thats the one youre trying to suppress. but ERβ

in the proliferative zone actually drives chondrocyte proliferation aka the thing that makes you grow. so when u run letrozole ur not selectively blocking

ERα ur just nuking all ur estrogen so both receptors lose signal at the same time. plates close slower yeah but they also grow slower bc u just killed the

signal telling ur chondrocytes to keep dividing. so the actual move is low dose AI to keep ERα quiet then throw in an ERβ selective agonist like s-equol or

liquiritigenin to restore the proliferative signal u just suppressed. stack that with abalo which is already holding chondrocytes in proliferative state via

pthrp and now u got three separate mechanisms all pushing in the same direction. running an AI without addressing ERβ is just leaving the most important

why is the saturation slowly leaving the words

 

[doidfestroyer]

why is the saturation slowly leaving the words

aesthetic

 

[BPnigga]

ok so everyone runs an AI on a height protocol bc estrogen closes plates right, makes sense. but heres the thing estrogen doesnt just bind to one receptor it

binds to ERα and ERβ and they do completely opposite things. ERα in the hypertrophic zone drives closure thats the one youre trying to suppress. but ERβ

in the proliferative zone actually drives chondrocyte proliferation aka the thing that makes you grow. so when u run letrozole ur not selectively blocking

ERα ur just nuking all ur estrogen so both receptors lose signal at the same time. plates close slower yeah but they also grow slower bc u just killed the

signal telling ur chondrocytes to keep dividing. so the actual move is low dose AI to keep ERα quiet then throw in an ERβ selective agonist like s-equol or

liquiritigenin to restore the proliferative signal u just suppressed. stack that with abalo which is already holding chondrocytes in proliferative state via

pthrp and now u got three separate mechanisms all pushing in the same direction. running an AI without addressing ERβ is just leaving the most important

Lmk how it goes

 

[brootaldood]

so with this information what would be the ideal stack for height?

 

[user20266741]

Can you make a thread explaining why I should pin 500grams of white sugar for bone growth?
Make it high iq like this one please

 

[doidfestroyer]

so with this information what would be the ideal stack for height?

idk abt ideal stack but you should add an ERb agonist to whatever your taking if u have an AI in it.