Chintuck22
Living like there's no tomorrow
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- May 16, 2019
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First, what is CAG length
"Male germ cell development can be divided into distinct stages, each representing a time window of susceptibility to epigenetic alterations, resulting in specific epigenetic changes in descendants and their phenotypes".
Exogenous anti-androgens changes the expression of your genetics (epigenetics), namely the repeat of CAG, leading to less androgen receptors in cells, leading to less protein synthesis from androgen receptor-dependent cells such as sperm.
- Can someone access the full PDF though @Lifeisgood72 @Dr Shekelberg @Mayorga ?
"Men with longer CAG repeats suffer from all sorts of performance handicaps compared to their short-CAG cohorts. Lengthening of CAG repeats may contribute toward decreased muscle mass, increased body fat, weaker bones, decreased aggressiveness, increased depression, reduced insulin sensitivity, and harm cardiovascular health through elevations in heart rate and blood pressure"
Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health
In this Review, the authors summarize current knowledge of sperm-specific epigenetic signatures and diet-induced epigenetic effects on sperm quality. They also discuss transgenerational effects of the sperm epigenome on offspring health.
www.nature.com
Exogenous anti-androgens changes the expression of your genetics (epigenetics), namely the repeat of CAG, leading to less androgen receptors in cells, leading to less protein synthesis from androgen receptor-dependent cells such as sperm.
- Can someone access the full PDF though @Lifeisgood72 @Dr Shekelberg @Mayorga ?