Concerns about SAM-e (heightmaxxing, pubertymaxxing, height)

[Corpuscula]

Im gonna use it as part of my stack for DNA Methylation for height purposes but I find in a study that Excess SAM-e inhibits DNA Methylation which is the opposite of what we want.
Then, the study says that by « excess » they meant more than 1Mm/L of exogenous SAM-e, I asked AI whatever that meant and it said it’s 0.399g/L so around 40mg, yet all supplements of SAMe give at least 200mg and most heightstacks recommend fricking 1500mg per day.
That’s why I made this post, please tell me if I got something wrong, if it’s actually safe or… if I’m right..

 

[MyDreamIsToBe183CM]

What’s ur stack rn

Im gonna use it as part of my stack for DNA Methylation for height purposes but I find in a study that Excess SAM-e inhibits DNA Methylation which is the opposite of what we want.
Then, the study says that by « excess » they meant more than 1Mm/L of exogenous SAM-e, I asked AI whatever that meant and it said it’s 0.399g/L so around 40mg, yet all supplements of SAMe give at least 200mg and most heightstacks recommend fricking 1500mg per day.
That’s why I made this post, please tell me if I got something wrong, if it’s actually safe or… if I’m right..

 

[Corpuscula]

What’s ur stack rn

I don’t really have one yet, it’s getting delivered soon, (chondroitin, MSM, glucosamine, SAM-e) rn I just use 50mg Zinc before bed praying that it inhibits aromatase (I’m poor) when I turn 16 in a month I’ll be able to work and buy an actual AI and HGH and make a real stack

 

[Kostas]

If you decide to use it, make sure you are supplementing its co-factor nutrients: methylfolate, Methyl B12, and B6 (P5P). These nutrients are important for the methylation cycle in general.

For preventing over-methylation (which is bound to happen at some point when you supplement methyl donors but not in the way you mentioned), you need to make sure your glycine buffer system is working: vitamin A, Adequate glycine, iron, riboflavin, and folate are needed. This will also help to store excess methyl groups & retrieve them when you need them.

 

[Corpuscula]

If you decide to use it, make sure you are supplementing its co-factor nutrients: methylfolate, Methyl B12, and B6 (P5P). These nutrients are important for the methylation cycle in general.

For preventing over-methylation (which is bound to happen at some point when you supplement methyl donors but not in the way you mentioned), you need to make sure your glycine buffer system is working: vitamin A, Adequate glycine, iron, riboflavin, and folate are needed. This will also help to store excess methyl groups & retrieve them when you need them.

where'd u get those info from

 

[Kostas]

where'd u get those info from

I've had an interest in methylation and have read lot's on it

 

[MA_ascender]

Don't waste your time with this bullshit just save until you can get test and some cheap peptides

 

[Corpuscula]

Im gonna use it as part of my stack for DNA Methylation for height purposes but I find in a study that Excess SAM-e inhibits DNA Methylation which is the opposite of what we want.
Then, the study says that by « excess » they meant more than 1Mm/L of exogenous SAM-e, I asked AI whatever that meant and it said it’s 0.399g/L so around 40mg, yet all supplements of SAMe give at least 200mg and most heightstacks recommend fricking 1500mg per day.
That’s why I made this post, please tell me if I got something wrong, if it’s actually safe or… if I’m right..

@Saint Casanova @moreplatesmoreweigh @wastedspermcel @sportsmogger @Gengar @Rigged @halloweed

 

[Corpuscula]

Don't waste your time with this bullshit just save until you can get test and some cheap peptides

yeah nah im not listening to someone telling me to get test for heightmaxxing

 

[MA_ascender]

yeah nah im not listening to someone telling me to get test for heightmaxxing

Low iq

 

[20/04/2008]

I don’t really have one yet, it’s getting delivered soon, (chondroitin, MSM, glucosamine, SAM-e) rn I just use 50mg Zinc before bed praying that it inhibits aromatase (I’m poor) when I turn 16 in a month I’ll be able to work and buy an actual AI and HGH and make a real stack

Nigga pm me
Ive been doin research on cheap over the counter aromatise inhibitors

 

[wastedspermcel]

Low iq

Eleman 2.0

 

[Corpuscula]

Low iq

how bro, you do know that all that testosterone will turn into estrogen right? that's why "hairy/short/male pattern baldness" exists

 

[MA_ascender]

Eleman 2.0

Androgens are meta boyo


Don't listen to dyorotic and hop on cattle drugs, test and some primo will do just fine

 

[MA_ascender]

how bro, you do know that all that testosterone will turn into estrogen right? that's why "hairy/short/male pattern baldness" exists

aromatase inhibitors exist


Let's just abandon the molecule that makes you taller broader and doubles your igf.

 

[Corpuscula]

aromatase inhibitors exist


Let's just abandon the molecule that makes you taller broader and doubles your igf.

nigga im obv gonna get an AI, I'm doing "all that" cuz i currently DONT have a job

 

[Corpuscula]

Nigga pm me
Ive been doin research on cheap over the counter aromatise inhibitors

checks dms

 

[MA_ascender]

Nigga pm me
Ive been doin research on cheap over the counter aromatise inhibitors

Cope.org

 

[20/04/2008]

Cope.org

Doing something is better than doing nothing

 

[Corpuscula]

Doing something is better than doing nothing

BRO LOOK AT UR DMS

 

[20/04/2008]

BRO LOOK AT UR DMS

Do a conversation much better

 

[Corpuscula]

Do a conversation much better

aint that the same thing

 

[Corpuscula]

Im gonna use it as part of my stack for DNA Methylation for height purposes but I find in a study that Excess SAM-e inhibits DNA Methylation which is the opposite of what we want.
Then, the study says that by « excess » they meant more than 1Mm/L of exogenous SAM-e, I asked AI whatever that meant and it said it’s 0.399g/L so around 40mg, yet all supplements of SAMe give at least 200mg and most heightstacks recommend fricking 1500mg per day.
That’s why I made this post, please tell me if I got something wrong, if it’s actually safe or… if I’m right..

bump

 

[Corpuscula]

checks dms

 

[moreplatesmoreweigh]

Dude there’s no proof that dna methylation will alter the gene you want jfl unless it’s a compound that directly causes gene methylation like aas

 

[Corpuscula]

Dude there’s no proof that dna methylation will alter the gene you want jfl unless it’s a compound that directly causes gene methylation like aas

i dont want to alter nun, "growth plate senescense is associated with loss of DNA methylation" = gain back DNA methylation = no more growth plate senescence (or possibly reverse it, we don't know yet)

 

[AySab]

Im gonna use it as part of my stack for DNA Methylation for height purposes but I find in a study that Excess SAM-e inhibits DNA Methylation which is the opposite of what we want.
Then, the study says that by « excess » they meant more than 1Mm/L of exogenous SAM-e, I asked AI whatever that meant and it said it’s 0.399g/L so around 40mg, yet all supplements of SAMe give at least 200mg and most heightstacks recommend fricking 1500mg per day.
That’s why I made this post, please tell me if I got something wrong, if it’s actually safe or… if I’m right..

you shouldn’t do this as you’ll probably force your body into a hypermethylated state. It also will not be effective enough, if it were, then it would be used for treating idiopathic short stature.

 

[AySab]

Nigga pm me
Ive been doin research on cheap over the counter aromatise inhibitors

lmfao.

 

[20/04/2008]

lmfao.

 

[Corpuscula]

you shouldn’t do this as you’ll probably force your body into a hypermethylated state. It also will not be effective enough, if it were, then it would be used for treating idiopathic short stature.

"To match the daily recommended intake of SAM supplements of 0.8–1.6 g/day in human, we administered SAM to mice at a concentration of 100 and 250 mg/kg of food, and monitored circadian locomotor (running wheel) activity rhythms in constant darkness for around 1 month to allow expression of endogenous rhythms. At both 100 and 250 mg/kg, SAM caused an increase in the circadian period compared to control, with a dose-dependent effect seen by an increase in the CTL vs. SAM significance in post hoc analysis (Fig. 6)." My supplement has 200mg of SAMe per capsule so it should be fine