Looksmax EMPTYING MY ANTI-BALDING FOLDER

Chintuck22

Chintuck22

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What effects balding?

- So the balding is caused by androgenic alopecia and many other things that we should pay attention on to when we talk about balding...


  • DHT alopecia
  • DNA methylation
  • Folicle acidosis (not finished)
  • Circulation
  • SM04554



DISCLAIMER

- We are not going to be using finasteride or minox, simply because fin nukes your DHT production by around 60% by taking 1 mg of or 90% by taking 5 mg of dutasteride. Also, finasteride damages more than 10,000 genes, so it’s not worth taking it either way.


---------------------------------------------------------------


DHT ALOPECIA

Is caused by high DHT production, but we shouldn't lower our androgens in hope to reverse balding, because it is couterproductive - Your primary sexual functions are dependent on your androgenic hormones. Topical RU58841 can .. and doesn't shutdown your androgen production like fin or dut.





DNA Methylation



The effects of IGF-1 on the hair growth:
  • Increase blood flow of hair root
  • Promotion of hair growth and hair restoration
  • Prevention of hair loss
  • Melanin hyperpigmentation of hair
  • Enhance hair dryness and luster


What is AR gene methylation?


-> DNA methylation is a biological process of adding a methyl group to DNA.
In this case, adding a methyl group to the CpG island in the promoter region of the androgen receptor gene in hair follicles will reduce its expression. Think of it as an on/off switch and methylation turns gene expression off.

A common characteristic of MPB (male pattern baldness) is that it affects the top of the head (vertex) much more than the back of the head (occiput). This is because vertex hair follicles have much lower levels of methylation than occipital hair follicles and thus are a lot more sensitive to DHT. Occipital hair follicles have twice the amount of methylation, on average. Hence, the occiput is not affected as much from MPB.

If hormones really were to blame (they are not), you‘d see androgenetic alopecia begin in puberty and improve with the decline of men‘s T levels as they age and gain weight. But this isn‘t the case. It usually begins in one‘s mid- to late twenties or later in life and does not resolve on its own.
The real cause of AGA is a gradual decline in DNA methylation, which is also heavily involved in aging and the onset of diseases and cancer in general. So, instead of removing the signal (DHT) from the overactive androgen receptors, we should normalize their expression. If it works in puberty - lots of androgens but healthy levels of methylation = no hair loss - it‘ll work at any age. DHT does not matter. You need it for well-being. No more jewtasteride.

Tl;dr: If you want to keep your hair, increase methylation.
How? Take:


• riboflavin
• vitamin B6 as P-5-P
• vitamin B9 as L-5-MTHF
• vitamin B12 as methylcobalamin
• vitamin C
• vitamin A, D, K2 + magnesium
(• SAMe)
(• TMG (betaine))
• diet rich in (trace) minerals and with plenty of protein and choline.







Circulation

So the bad circulation is responsible (in one way) for fibrosis, artery contraction, reduced blood flow, tension, calcification and ultimately inflammation. These syptoms act on pathway and genes, and they are, like i said - responsible for hair loss in one hand. What can we do about it? -

——————————-
-DermaPen / Dermarolling

-Apple cider vinegar
-Onion juice
-Garlic Juice

-Eat a nutrient dense diet full of vit D3, K2, Magnesium Omega 3..

——————————-
- You can dislute: Castor Oil, Coconut Oil, Almond Oil, Jojoba Oil, Emu Oil, Vitamin E, Brahmi/Alma Oil, Pumkin Seed Oil, Lavender Oil, Rosemary Oil, Peppermint Oil, TeaTree Oil (lazy to elab each one of them, proven to thicken and regrow hair a bit, slow shedding and hair loss, can lower DHT locally, etc (don't be concerned about it).








SM04554 phase 3 treatment for hair loss


The geniuses at samumed were able to isolate a molecule to cure the hairloss disease without any side effects and the phase 1&2 clinical trials have been nothing short of a miracle. Unfortunately since Male Pattern Baldness isn't treated as a "Life Threatening disease", sm04554 will most likely be the singlemost expensive treatment that has ever existed, due to the extreme inelastic demand and the fact that you won't literally "die" if you're not treated. Bald CEOs are probably very eager for this.



SM04554 + Microneedling ?

Almost all scalp hair loss is caused by inflammation of the follicle bulbs in the scalp. The inflammation causes micro-scarring (fibrosis), leaving the hair follicles irreversibly damaged.

Needling works by replacing the scarred tissue with fresh new tissue, by forcing the skin to generate completely new tissue. You can use the skin’s natural healing mechanism to grow new tissue: and in the new tissue, new hair follicles will form.



Needling alone will not really cause new hair follicles to generate. - You also need to increase specific ‘growth factors’ in the scalp tissue. These are like chemical messengers which tell the newly forming tissue to generate new hair follicles, instead of just skin. This is called ‘hair follicle neogenesis’. It’s very important that you use the right growth factors. Some growth factors make your hair stop growing and some make it grow.

One of those Growth-Factors is Minoxidil, which increase hair growth by increasing the growth factor VEGF, which helps maintain the blood vessels that connect to the hair follicles.

But there will be a new Contestor in the future which should also be good for the skin:
SM04554, a WnT Pathway modulator.

- Once the growth factors are in the healing tissue they send intra-cellular chemical messages, telling the cells which type of new tissue to form. By using the right growth factors you can encourage hair follicles to form.



The WnT Pathway is also the main contributor to hair growth and the power-house of the Anagen-Phase in the hair-cycle



I can understand that people don't want to use Minoxidil, but atleast start with the Needling
There are already several success stories with needling, also on Lookism.








OR YOU CAN GET HAIR TRANSPLANT AND WORRY NONE ABOUT THESE THINGS.
 
Deleted member 7776

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First

edit: Great thread. You missed a lot of treatment options tho.

Edit2: It's very interesting to me that I had had very bad scalp pain and inflammation for months.. Then I washed my hair with ketoconazole just once and the next day my pain disappeared completely. I've been using keto 2x a week ever since.
 
nonserviam

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banger thread tbh, but prolly is cope
also wtf does dislute mean ?
 
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nonserviam said:
banger thread tbh, but prolly is cope
also wtf does dislute mean ?
dilute lol
 
Dr. Greenberg

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Just pray to Pitt
 
Chintuck22

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thinwhiteduke said:
one chin tuck a day keeping my balding away
One rope a day makes the pain go away
 
ShineBright

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Either waste an hour everyday rubbing expensive creams and rolling needles across your head (usually for months before seeing any results) while also taking pills that may or may not break your dick & sex drive

OR

Hair transplant
 
poloralf

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Prood that samused is a cure and not minox tier cope ?
 
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just steal Bewusst @Bewusst thread
 
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Chintuck22 said:
What effects balding?

- So the balding is caused by androgenic alopecia and many other things that we should pay attention on to when we talk about balding...


  • DHT alopecia
  • DNA methylation
  • Folicle acidosis (not finished)
  • Circulation
  • SM04554



DISCLAIMER

- We are not going to be using finasteride or minox, simply because fin nukes your DHT production by around 60% by taking 1 mg of or 90% by taking 5 mg of dutasteride. Also, finasteride damages more than 10,000 genes, so it’s not worth taking it either way.


---------------------------------------------------------------



DHT ALOPECIA

Is caused by high DHT production, but we shouldn't lower our androgens in hope to reverse balding, because it is couterproductive - Your primary sexual functions are dependent on your androgenic hormones. Topical RU58841 can .. and doesn't shutdown your androgen production like fin or dut.





DNA Methylation




The effects of IGF-1 on the hair growth:
  • Increase blood flow of hair root
  • Promotion of hair growth and hair restoration
  • Prevention of hair loss
  • Melanin hyperpigmentation of hair
  • Enhance hair dryness and luster


What is AR gene methylation?

-> DNA methylation is a biological process of adding a methyl group to DNA.
In this case, adding a methyl group to the CpG island in the promoter region of the androgen receptor gene in hair follicles will reduce its expression. Think of it as an on/off switch and methylation turns gene expression off.

A common characteristic of MPB (male pattern baldness) is that it affects the top of the head (vertex) much more than the back of the head (occiput). This is because vertex hair follicles have much lower levels of methylation than occipital hair follicles and thus are a lot more sensitive to DHT. Occipital hair follicles have twice the amount of methylation, on average. Hence, the occiput is not affected as much from MPB.

If hormones really were to blame (they are not), you‘d see androgenetic alopecia begin in puberty and improve with the decline of men‘s T levels as they age and gain weight. But this isn‘t the case. It usually begins in one‘s mid- to late twenties or later in life and does not resolve on its own.
The real cause of AGA is a gradual decline in DNA methylation, which is also heavily involved in aging and the onset of diseases and cancer in general. So, instead of removing the signal (DHT) from the overactive androgen receptors, we should normalize their expression. If it works in puberty - lots of androgens but healthy levels of methylation = no hair loss - it‘ll work at any age. DHT does not matter. You need it for well-being. No more jewtasteride.


Tl;dr: If you want to keep your hair, increase methylation.
How? Take:


• riboflavin
• vitamin B6 as P-5-P
• vitamin B9 as L-5-MTHF
• vitamin B12 as methylcobalamin
• vitamin C
• vitamin A, D, K2 + magnesium
(• SAMe)
(• TMG (betaine))
• diet rich in (trace) minerals and with plenty of protein and choline.







Circulation

So the bad circulation is responsible (in one way) for fibrosis, artery contraction, reduced blood flow, tension, calcification and ultimately inflammation. These syptoms act on pathway and genes, and they are, like i said - responsible for hair loss in one hand. What can we do about it? -

——————————-
-DermaPen / Dermarolling

-Apple cider vinegar
-Onion juice
-Garlic Juice

-Eat a nutrient dense diet full of vit D3, K2, Magnesium Omega 3..

——————————-
- You can dislute: Castor Oil, Coconut Oil, Almond Oil, Jojoba Oil, Emu Oil, Vitamin E, Brahmi/Alma Oil, Pumkin Seed Oil, Lavender Oil, Rosemary Oil, Peppermint Oil, TeaTree Oil (lazy to elab each one of them, proven to thicken and regrow hair a bit, slow shedding and hair loss, can lower DHT locally, etc (don't be concerned about it).









SM04554 phase 3 treatment for hair loss


The geniuses at samumed were able to isolate a molecule to cure the hairloss disease without any side effects and the phase 1&2 clinical trials have been nothing short of a miracle. Unfortunately since Male Pattern Baldness isn't treated as a "Life Threatening disease", sm04554 will most likely be the singlemost expensive treatment that has ever existed, due to the extreme inelastic demand and the fact that you won't literally "die" if you're not treated. Bald CEOs are probably very eager for this.

View attachment 732597 View attachment 732598


SM04554 + Microneedling ?

Almost all scalp hair loss is caused by inflammation of the follicle bulbs in the scalp. The inflammation causes micro-scarring (fibrosis), leaving the hair follicles irreversibly damaged.

Needling works by replacing the scarred tissue with fresh new tissue, by forcing the skin to generate completely new tissue. You can use the skin’s natural healing mechanism to grow new tissue: and in the new tissue, new hair follicles will form.



Needling alone will not really cause new hair follicles to generate. - You also need to increase specific ‘growth factors’ in the scalp tissue. These are like chemical messengers which tell the newly forming tissue to generate new hair follicles, instead of just skin. This is called ‘hair follicle neogenesis’. It’s very important that you use the right growth factors. Some growth factors make your hair stop growing and some make it grow.

One of those Growth-Factors is Minoxidil, which increase hair growth by increasing the growth factor VEGF, which helps maintain the blood vessels that connect to the hair follicles.

But there will be a new Contestor in the future which should also be good for the skin:
SM04554, a WnT Pathway modulator.

- Once the growth factors are in the healing tissue they send intra-cellular chemical messages, telling the cells which type of new tissue to form. By using the right growth factors you can encourage hair follicles to form.



The WnT Pathway is also the main contributor to hair growth and the power-house of the Anagen-Phase in the hair-cycle

View attachment 732599

I can understand that people don't want to use Minoxidil, but atleast start with the Needling
There are already several success stories with needling, also on Lookism.








OR YOU CAN GET HAIR TRANSPLANT AND WORRY NONE ABOUT THESE THINGS.
T levels can also cause hair loss
 
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OP je moj rodjeni brat 🤝
 
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Great thread, bookmarked and will read the rest later. I got a scalp biopsy and it said I had androgenic (dht) alopecia. I am a little obese but got t tested at 607ng/dl and cortisol tested at under the normal range. My question is, does dht production get affected by aromatase? I didn't get my dht tested in my blood work but clearly it's high enough to cause androgenic alopecia, I doubt 607ng/dl t can do that alone.
 
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TheEndHasNoEnd said:
Great thread, bookmarked and will read the rest later. I got a scalp biopsy and it said I had androgenic (dht) alopecia. I am a little obese but got t tested at 607ng/dl and cortisol tested at under the normal range. My question is, does dht production get affected by aromatase? I didn't get my dht tested in my blood work but clearly it's high enough to cause androgenic alopecia, I doubt 607ng/dl t can do that alone.
Is it high dht sensitivity?
 
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What do you think of this
Chintuck22 @Chintuck22
 
Pumanator

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Cope article.
MPB is causes by T, and DHT. Other reason may be inflammation or bad hormones levels like thyroid hormones (rare for males). There is however difference in andrognic sensitivity. Some people can blast trenbelone and have NW 0 hair and sometimes female get hair loss by DHT and T even their androgenic hormones levels are extremely low.

Supplementing certain nutrients (vitamins) only work when defficient. Having a normal diet should stop that.
Raising IGF-1 to stop hair loss only works when you are defficient. Going to high IGF-1 levels or superficial wont do shit.

Stopping ED can be known by proper bloodwork there is a high chance that free T dropped that cause problem. So TRT may be necessary.
You can nuke ur DHT by 99% and aslong you got sufficient T, side effects shouldn't be harsh or nonpresent. ED can be stoppen if enough T is present to compensate the lack of DHT. You shouldn't never drop DHT when you are below 23.

I dont know anything about SM0455 so I will dig into that. Dropping sensentivity to androgenic hormones like T and DHT will work to stop hair loss. However can it be done locally? Dropping it in muscles organs etc. Will be bad.

I am pretty sure that microneedling works cause of the better absorption. Minoxidil for example takes a few hours to absorb in the scalp and microneedling shortens it and makes sure more is absorbed.

Also hormones and aging is noticable since hair density decreases at 15/ 16. It's around 100.000 at peak. When you are 18 and it's for example 80.000 no one will notice but it's less hair then peak.

Also if hair loss is not causes by hormones but food, that would mean all the females have perfect diets and us males not.

I am afraid nature want alot of man to be bald and unless we intervene non naturally we cant stop hair loss. i would advice to try nature first, but in hair loss its giving males hope to stop it naturally while shedding every day.
 
Last edited:
D

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You're literally not even balding?
 
Chintuck22

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Gudru said:
You're literally not even balding?
Come on, i started 3 months ago
 
Ampere

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Currently on topical fin + min, working well, no side effects (well, idk if depression is cause of fina or shit life, idc anyway :lul:)

I've read about RU58841 before but don't remember SM04554, will look into it but tbh I have zero sexual sides I can still do multiple NEO in a row and stay hard :lul:

But yeah I have hopes that in a few years we finally will have better alternatives to finasteride and minox
 
MansNotHot

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Pumanator said:
Cope article.
MPB is causes by T, and DHT. Other reason may be inflammation or bad hormones levels like thyroid hormones (rare for males). There is however difference in andrognic sensitivity. Some people can blast trenbelone and have NW 0 hair and sometimes female get hair loss by DHT and T even their androgenic hormones levels are extremely low.

Supplementing certain nutrients (vitamins) only work when defficient. Having a normal diet should stop that.
Raising IGF-1 to stop hair loss only works when you are defficient. Going to high IGF-1 levels or superficial wont do shit.

Stopping ED can be known by proper bloodwork there is a high chance that free T dropped that cause problem. So TRT may be necessary.
You can nuke ur DHT by 99% and aslong you got sufficient T, side effects shouldn't be harsh or nonpresent. ED can be stoppen if enough T is present to compensate the lack of DHT. You shouldn't never drop DHT when you are below 23.

I dont know anything about SM0455 so I will dig into that. Dropping sensentivity to androgenic hormones like T and DHT will work to stop hair loss. However can it be done locally? Dropping it in muscles organs etc. Will be bad.

I am pretty sure that microneedling works cause of the better absorption. Minoxidil for example takes a few hours to absorb in the scalp and microneedling shortens it and makes sure more is absorbed.

Also hormones and aging is noticable since hair density decreases at 15/ 16. It's around 100.000 at peak. When you are 18 and it's for example 80.000 no one will notice but it's less hair then peak.

Also if hair loss is not causes by hormones but food, that would mean all the females have perfect diets and us males not.

I am afraid nature want alot of man to be bald and unless we intervene non naturally we cant stop hair loss. i would advice to try nature first, but in hair loss its giving males hope to stop it naturally while shedding every day.
Exactly what i said above, i second this.
 
CopeTilliRope

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that's exactly the reason why i don't browse this forum anymore ... no offense but again a cope thread made by a guy who started balding 3 months ago and who recommend using RU an unknow chemical with no data concerning the long term safrty profile and absorption who got dropped by roussel for no reason over fda proven medication such as fin ( don't get me wrong fin sucks and won't stop agressive balding).

and what's more funny is that you truly believe sm 'd be able to strop agressive aga over antiandrogens

btw i just had a phone call with evelyne guenole who was supervizing the psk3841 study and told and she told me we shouldn't even touch the RU we can get on our hands on the net
 
CopeTilliRope

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MansNotHot said:
Cope

Hair loss--->Dht
Dht-->useless hormone after puberty
Finasteride-->only medically tested, FDA approved (temporary cure)

This thread--->pseudoscience
this godamn this forum knows shit about hairloss
 
MansNotHot

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CopeTilliRope said:
this godamn this forum knows shit about hairloss
What do you expect from 12 yr olds tbh.
Speaking as a 17 yo 😂
 
Chintuck22

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Brb taking shit
 
Last edited:
Chintuck22

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CopeTilliRope said:
this godamn this forum knows shit about hairloss
You are shit, get the fuck out of my thread, this is all you fucking needed..

What did you excpected me to write? You lobotomized braindead corpse
 
eduardkoopman

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Chintuck22 said:
SM04554 phase 3 treatment for hair loss
lifefuel, for balding. Sad can't buy it illegally yet.
 
CopeTilliRope

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eduardkoopman said:
lifefuel, for balding. Sad can't buy it illegally yet.
https://thekaneshop.com/product/sm04554/ enjoy and dn't forget to add some RU and other unproven chemicals
 
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You didnt mention taurine. You are not even trying.
 
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ablanc10 said:
You didnt mention taurine. You are not even trying.
Was that ramblings of a schiophrenic patient ?
 
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Chintuck22 said:
Okay, thx bro
shit i put in the wrong link but i fixed it
 
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Chintuck22 said:
Was that ramblings of a schiophrenic patient ?
No, but keep mirin my hair bro.
 
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I got fucked by genes and DHT.

Dad and his brothers start to lose hair in their 50s, none are above NW2. Paternal grandfather died in his 60s while still having hair (NW2).
Mom's brothers bald early, most are NW3+ before 50yo. Maternal grandfather was completely bald on the top of the head.
Cousins from my mother side bald more than cousins from my dad side. Both side of the family eat like shit (western diet) and most of them are overweight.

I'm fucked by the genes I got from my mom. I have many androgen receptors in my skin or I'm highly sensitive to androgens: my skin is oily, I can grow a full beard, I'm hairy everywhere (not on the back tho), prone to acne...

I have 3 bros and one of them started balding sooner than us (before 20yo). He is also the bro with the deepest voice, highest body height and biggest dick (judging from bulge, I did not saw it directly). Coincidence?
 
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Chintuck22 said:
Needling alone will not really cause new hair follicles to generate. - You also need to increase specific ‘growth factors’ in the scalp tissue. These are like chemical messengers which tell the newly forming tissue to generate new hair follicles, instead of just skin. This is called ‘hair follicle neogenesis’. It’s very important that you use the right growth factors. Some growth factors make your hair stop growing and some make it grow.

One of those Growth-Factors is Minoxidil, which increase hair growth by increasing the growth factor VEGF, which helps maintain the blood vessels that connect to the hair follicles.
more on this? anything else that can be used? right after needling or when? god bless tyty
 
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going to have a wank to this thread later, dangerously based
 
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Chintuck22 said:
The geniuses at samumed were able to isolate a molecule to cure the hairloss disease without any side effects and the phase 1&2 clinical trials have been nothing short of a miracle. Unfortunately since Male Pattern Baldness isn't treated as a "Life Threatening disease", sm04554 will most likely be the singlemost expensive treatment that has ever existed, due to the extreme inelastic demand and the fact that you won't literally "die" if you're not treated. Bald CEOs are probably very eager for this.
I said all this word for word jfl where's the credit :p
 
LooksmaxxHopeful

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Chintuck22 said:
What effects balding?

- So the balding is caused by androgenic alopecia and many other things that we should pay attention on to when we talk about balding...


  • DHT alopecia
  • DNA methylation
  • Folicle acidosis (not finished)
  • Circulation
  • SM04554



DISCLAIMER

- We are not going to be using finasteride or minox, simply because fin nukes your DHT production by around 60% by taking 1 mg of or 90% by taking 5 mg of dutasteride. Also, finasteride damages more than 10,000 genes, so it’s not worth taking it either way.


---------------------------------------------------------------



DHT ALOPECIA

Is caused by high DHT production, but we shouldn't lower our androgens in hope to reverse balding, because it is couterproductive - Your primary sexual functions are dependent on your androgenic hormones. Topical RU58841 can .. and doesn't shutdown your androgen production like fin or dut.





DNA Methylation




The effects of IGF-1 on the hair growth:
  • Increase blood flow of hair root
  • Promotion of hair growth and hair restoration
  • Prevention of hair loss
  • Melanin hyperpigmentation of hair
  • Enhance hair dryness and luster


What is AR gene methylation?

-> DNA methylation is a biological process of adding a methyl group to DNA.
In this case, adding a methyl group to the CpG island in the promoter region of the androgen receptor gene in hair follicles will reduce its expression. Think of it as an on/off switch and methylation turns gene expression off.

A common characteristic of MPB (male pattern baldness) is that it affects the top of the head (vertex) much more than the back of the head (occiput). This is because vertex hair follicles have much lower levels of methylation than occipital hair follicles and thus are a lot more sensitive to DHT. Occipital hair follicles have twice the amount of methylation, on average. Hence, the occiput is not affected as much from MPB.

If hormones really were to blame (they are not), you‘d see androgenetic alopecia begin in puberty and improve with the decline of men‘s T levels as they age and gain weight. But this isn‘t the case. It usually begins in one‘s mid- to late twenties or later in life and does not resolve on its own.
The real cause of AGA is a gradual decline in DNA methylation, which is also heavily involved in aging and the onset of diseases and cancer in general. So, instead of removing the signal (DHT) from the overactive androgen receptors, we should normalize their expression. If it works in puberty - lots of androgens but healthy levels of methylation = no hair loss - it‘ll work at any age. DHT does not matter. You need it for well-being. No more jewtasteride.


Tl;dr: If you want to keep your hair, increase methylation.
How? Take:


• riboflavin
• vitamin B6 as P-5-P
• vitamin B9 as L-5-MTHF
• vitamin B12 as methylcobalamin
• vitamin C
• vitamin A, D, K2 + magnesium
(• SAMe)
(• TMG (betaine))
• diet rich in (trace) minerals and with plenty of protein and choline.







Circulation

So the bad circulation is responsible (in one way) for fibrosis, artery contraction, reduced blood flow, tension, calcification and ultimately inflammation. These syptoms act on pathway and genes, and they are, like i said - responsible for hair loss in one hand. What can we do about it? -

——————————-
-DermaPen / Dermarolling

-Apple cider vinegar
-Onion juice
-Garlic Juice

-Eat a nutrient dense diet full of vit D3, K2, Magnesium Omega 3..

——————————-
- You can dislute: Castor Oil, Coconut Oil, Almond Oil, Jojoba Oil, Emu Oil, Vitamin E, Brahmi/Alma Oil, Pumkin Seed Oil, Lavender Oil, Rosemary Oil, Peppermint Oil, TeaTree Oil (lazy to elab each one of them, proven to thicken and regrow hair a bit, slow shedding and hair loss, can lower DHT locally, etc (don't be concerned about it).









SM04554 phase 3 treatment for hair loss


The geniuses at samumed were able to isolate a molecule to cure the hairloss disease without any side effects and the phase 1&2 clinical trials have been nothing short of a miracle. Unfortunately since Male Pattern Baldness isn't treated as a "Life Threatening disease", sm04554 will most likely be the singlemost expensive treatment that has ever existed, due to the extreme inelastic demand and the fact that you won't literally "die" if you're not treated. Bald CEOs are probably very eager for this.

View attachment 732597 View attachment 732598


SM04554 + Microneedling ?

Almost all scalp hair loss is caused by inflammation of the follicle bulbs in the scalp. The inflammation causes micro-scarring (fibrosis), leaving the hair follicles irreversibly damaged.

Needling works by replacing the scarred tissue with fresh new tissue, by forcing the skin to generate completely new tissue. You can use the skin’s natural healing mechanism to grow new tissue: and in the new tissue, new hair follicles will form.



Needling alone will not really cause new hair follicles to generate. - You also need to increase specific ‘growth factors’ in the scalp tissue. These are like chemical messengers which tell the newly forming tissue to generate new hair follicles, instead of just skin. This is called ‘hair follicle neogenesis’. It’s very important that you use the right growth factors. Some growth factors make your hair stop growing and some make it grow.

One of those Growth-Factors is Minoxidil, which increase hair growth by increasing the growth factor VEGF, which helps maintain the blood vessels that connect to the hair follicles.

But there will be a new Contestor in the future which should also be good for the skin:
SM04554, a WnT Pathway modulator.

- Once the growth factors are in the healing tissue they send intra-cellular chemical messages, telling the cells which type of new tissue to form. By using the right growth factors you can encourage hair follicles to form.



The WnT Pathway is also the main contributor to hair growth and the power-house of the Anagen-Phase in the hair-cycle

View attachment 732599

I can understand that people don't want to use Minoxidil, but atleast start with the Needling
There are already several success stories with needling, also on Lookism.








OR YOU CAN GET HAIR TRANSPLANT AND WORRY NONE ABOUT THESE THINGS.
I have ADHD can't read all this too long, I bookmarked it though, I have good hair but I'll probably just get on a finasteride routine once I'm 22 or something just to be safe/proactive.

I want to maintain my mogger nw0 hairline and density into my 40s :feelshehe:
 
R

Rift678

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All of this is utter cope if you have MPB. You need fin period
 

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