Chintuck22
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What effects balding?
- So the balding is caused by androgenic alopecia and many other things that we should pay attention on to when we talk about balding...
- So the balding is caused by androgenic alopecia and many other things that we should pay attention on to when we talk about balding...
- DHT alopecia
- DNA methylation
- Folicle acidosis (not finished)
- Circulation
- SM04554
DISCLAIMER
- We are not going to be using finasteride or minox, simply because fin nukes your DHT production by around 60% by taking 1 mg of or 90% by taking 5 mg of dutasteride. Also, finasteride damages more than 10,000 genes, so it’s not worth taking it either way.
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⚠ DHT ALOPECIA ⚠
Is caused by high DHT production, but we shouldn't lower our androgens in hope to reverse balding, because it is couterproductive - Your primary sexual functions are dependent on your androgenic hormones. Topical RU58841 can .. and doesn't shutdown your androgen production like fin or dut.
⚠ DNA Methylation ⚠
- We are not going to be using finasteride or minox, simply because fin nukes your DHT production by around 60% by taking 1 mg of or 90% by taking 5 mg of dutasteride. Also, finasteride damages more than 10,000 genes, so it’s not worth taking it either way.
---------------------------------------------------------------
⚠ DHT ALOPECIA ⚠
Is caused by high DHT production, but we shouldn't lower our androgens in hope to reverse balding, because it is couterproductive - Your primary sexual functions are dependent on your androgenic hormones. Topical RU58841 can .. and doesn't shutdown your androgen production like fin or dut.
⚠ DNA Methylation ⚠
The effects of IGF-1 on the hair growth:
- Increase blood flow of hair root
- Promotion of hair growth and hair restoration
- Prevention of hair loss
- Melanin hyperpigmentation of hair
- Enhance hair dryness and luster
What is AR gene methylation?
-> DNA methylation is a biological process of adding a methyl group to DNA.
In this case, adding a methyl group to the CpG island in the promoter region of the androgen receptor gene in hair follicles will reduce its expression. Think of it as an on/off switch and methylation turns gene expression off.
A common characteristic of MPB (male pattern baldness) is that it affects the top of the head (vertex) much more than the back of the head (occiput). This is because vertex hair follicles have much lower levels of methylation than occipital hair follicles and thus are a lot more sensitive to DHT. Occipital hair follicles have twice the amount of methylation, on average. Hence, the occiput is not affected as much from MPB.
If hormones really were to blame (they are not), you‘d see androgenetic alopecia begin in puberty and improve with the decline of men‘s T levels as they age and gain weight. But this isn‘t the case. It usually begins in one‘s mid- to late twenties or later in life and does not resolve on its own.
The real cause of AGA is a gradual decline in DNA methylation, which is also heavily involved in aging and the onset of diseases and cancer in general. So, instead of removing the signal (DHT) from the overactive androgen receptors, we should normalize their expression. If it works in puberty - lots of androgens but healthy levels of methylation = no hair loss - it‘ll work at any age. DHT does not matter. You need it for well-being. No more jewtasteride.
Tl;dr: If you want to keep your hair, increase methylation.
How? Take:
• riboflavin
• vitamin B6 as P-5-P
• vitamin B9 as L-5-MTHF
• vitamin B12 as methylcobalamin
• vitamin C
• vitamin A, D, K2 + magnesium
(• SAMe)
(• TMG (betaine))
• diet rich in (trace) minerals and with plenty of protein and choline.
⚠ Circulation ⚠
So the bad circulation is responsible (in one way) for fibrosis, artery contraction, reduced blood flow, tension, calcification and ultimately inflammation. These syptoms act on pathway and genes, and they are, like i said - responsible for hair loss in one hand. What can we do about it? -
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-DermaPen / Dermarolling
-Apple cider vinegar
-Onion juice
-Garlic Juice
-Eat a nutrient dense diet full of vit D3, K2, Magnesium Omega 3..
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- You can dislute: Castor Oil, Coconut Oil, Almond Oil, Jojoba Oil, Emu Oil, Vitamin E, Brahmi/Alma Oil, Pumkin Seed Oil, Lavender Oil, Rosemary Oil, Peppermint Oil, TeaTree Oil (lazy to elab each one of them, proven to thicken and regrow hair a bit, slow shedding and hair loss, can lower DHT locally, etc (don't be concerned about it).
⚠ SM04554 phase 3 treatment for hair loss ⚠
The geniuses at samumed were able to isolate a molecule to cure the hairloss disease without any side effects and the phase 1&2 clinical trials have been nothing short of a miracle. Unfortunately since Male Pattern Baldness isn't treated as a "Life Threatening disease", sm04554 will most likely be the singlemost expensive treatment that has ever existed, due to the extreme inelastic demand and the fact that you won't literally "die" if you're not treated. Bald CEOs are probably very eager for this.
SM04554 + Microneedling ?
Almost all scalp hair loss is caused by inflammation of the follicle bulbs in the scalp. The inflammation causes micro-scarring (fibrosis), leaving the hair follicles irreversibly damaged.
Needling works by replacing the scarred tissue with fresh new tissue, by forcing the skin to generate completely new tissue. You can use the skin’s natural healing mechanism to grow new tissue: and in the new tissue, new hair follicles will form.
Needling alone will not really cause new hair follicles to generate. - You also need to increase specific ‘growth factors’ in the scalp tissue. These are like chemical messengers which tell the newly forming tissue to generate new hair follicles, instead of just skin. This is called ‘hair follicle neogenesis’. It’s very important that you use the right growth factors. Some growth factors make your hair stop growing and some make it grow.
One of those Growth-Factors is Minoxidil, which increase hair growth by increasing the growth factor VEGF, which helps maintain the blood vessels that connect to the hair follicles.
But there will be a new Contestor in the future which should also be good for the skin:
SM04554, a WnT Pathway modulator.
- Once the growth factors are in the healing tissue they send intra-cellular chemical messages, telling the cells which type of new tissue to form. By using the right growth factors you can encourage hair follicles to form.
The WnT Pathway is also the main contributor to hair growth and the power-house of the Anagen-Phase in the hair-cycle
I can understand that people don't want to use Minoxidil, but atleast start with the Needling
There are already several success stories with needling, also on Lookism.
OR YOU CAN GET HAIR TRANSPLANT AND WORRY NONE ABOUT THESE THINGS.