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everyone can get a GF except me💔
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I found this and thought that it could be helpful for my ethnic looksmaxxers here. You can get most of them online&legal.
-->Ingredients with the red color are proven to work (if you believe youtubers before/after)
@SubhumanCurrycel @Face is everything
-->Ingredients with the red color are proven to work (if you believe youtubers before/after)
Ingredient | Description | How it works | Efficacy | Safe on darker skin? |
Arbutin | A hydroquinone derivative (glycosylated benzoquinone) extracted from the bearberry shrub. | Inhibits tyrosinase to prevent the formation of melanin. | Arbutin found to inhibit melanin production in B16 cells induced with alpha-MSH and decreases tyrosinase activity. Less effective than kojic acid. | Yes. |
Alpha-Arbutin | Alpha-Arbutin is an epimer of arbutin (4-hydroxyphenyl alpha-glucopyranoside) | Inhibits tyrosinase to prevent the formation of melanin. Said to have a stronger effect than arbutin. | Melanin synthesis was reduced to 40% with 250 microg of alpha-arbutin. | Yes. |
Magnesium ascorbyl phosphate | A stable vitamin C derivative | Suppresses melanin formation and protects against skin damage caused by UVB rays. | A significant lightening effect was seen clinically in 19 of 34 patients with melasma and solar lentigos. | Yes. |
Kojic acid | Derived from fungus | Suppresses tyrosinase activity. | Less efficacious than 2% hydroquinone. May cause contact dermatitis and erythema. | Yes. |
Retin A/ Tretinoin | Retinoic acid/Vitamin A acid | Boosts epidermal turnover, which promotes keratinocyte proliferation. Discharges epidermal melanin but not dermal melanin. | Tretinoin was used as monotherapy in a study on 38 African- American patients with melasma and 68-73% of patients improved. | Yes. |
Liquorice extract/Licorice extract | Glabridin | Inhibits tyrosinase activity (similar to kojic acid). | A combination product of 0.4% licorice extract, 0.05% betamethasone, and 0.05% retinoic acid was found to be effective in the treatment of melasma. | Yes. |
Hydroquinone | An industrial chemical | Inhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes. Also competes for tyrosine oxidation in active melanocytes. | One of the most effective inhibitors of melanogenesis in vitro and in vivo. Evidence of improvement is usually observed at 4-6 weeks. Tretinoin has been used to enhance the efficacy of hydroquinone. | Mostly safe, but risks exist. Exogenous ochronosis observed in black patients who have used high concentrations for years. Thus, it should be discontinued if no improvement occurs within 4-6 months. |
Mulberry extract | Derived from root of paper mulberry plant (Morus alba root). | Inhibits tyrosinase activity. | Low concentrations shown to inhibit tyrosinase activity. Significantly lower compared to the concentrations needed for kojic acid and hydroquinone. | Yes. |
Azelaic acid | Derived from yeast. | Inhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes. | A 20% concentration of azelaic acid is equivalent to 2% hydroquinone. However, azelaic acid has no lightening effect on normally pigmented skin, freckles, senile lentigines, and nevi. It has selective effects on only abnormal melanocytes. | Yes. |
Niacinamide | Vitamin B3, niacin, nicotinamide | Inhibits melanosome transfer from melanocytes to keratinocytes. | In skin culture tests, niacinamide significantly inhibited the transfer of melanosomes from melanocytes to keratinocytes (by 25–45%; p activity. | Yes. |
Salicylic acid | A beta hydroxy acid (BHA) used to make aspirin. | Increases cell turnover. | Effective on minor skin discolorations. | Yes, in lower concentrations only. |
Undecylenoyl phenylalanine | Amino acid derivative. Commercial names include Skinwhite MSH and Sepiwhite MSH. | Acts as an antagonist to melanocyte stimulating hormone (MSH). Prevents the start of melanin synthesis. | In testing, melanin levels were significantly reduced by 53% after 13 days. | Yes. |
Topical corticosteroids | Several forms of corticosteroids include Hydrocortisone, Clobetasol Propionate, Fluocinolone Acetonide or Betamethasone Dipropionate. | Unknown. It is possible that steroids reduce the production of melanocyte stimulating hormones (MSH). | Fast temporary skin lightening, but prolonged use is dangerous. | No. |
Monobenzone | Monobenzyl ether of hydroquinone | Permanently depigments normal skin. | Used for vitiligo patients. | Used for vitiligo patients only. |
Mequinol | Monomethyl ether of hydroquinone | Cytotoxic to melanocytes. | Can be effective when used in conjunction with tretinoin. | Yes, in lower concentrations only. |
@SubhumanCurrycel @Face is everything