Every known Chemical/Cream/Oil to Lighten the Skin

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I found this and thought that it could be helpful for my ethnic looksmaxxers here. You can get most of them online&legal.
-->Ingredients with the red color are proven to work (if you believe youtubers before/after)



IngredientDescriptionHow it worksEfficacySafe on darker skin?
ArbutinA hydroquinone derivative (glycosylated benzoquinone) extracted from the bearberry shrub.Inhibits tyrosinase to prevent the formation of melanin.Arbutin found to inhibit melanin production in B16 cells induced with alpha-MSH and decreases tyrosinase activity. Less effective than kojic acid.Yes.
Alpha-ArbutinAlpha-Arbutin is an epimer of arbutin (4-hydroxyphenyl alpha-glucopyranoside)Inhibits tyrosinase to prevent the formation of melanin. Said to have a stronger effect than arbutin.Melanin synthesis was reduced to 40% with 250 microg of alpha-arbutin.Yes.
Magnesium ascorbyl phosphateA stable vitamin C derivativeSuppresses melanin formation and protects against skin damage caused by UVB rays.A significant lightening effect was seen clinically in 19 of 34 patients with melasma and solar lentigos.Yes.
Kojic acidDerived from fungusSuppresses tyrosinase activity.Less efficacious than 2% hydroquinone.

May cause contact dermatitis and erythema.
Yes.
Retin A/
Tretinoin
Retinoic acid/Vitamin A acidBoosts epidermal turnover, which promotes keratinocyte proliferation. Discharges epidermal melanin but not dermal melanin.Tretinoin was used as monotherapy in a study on 38 African- American patients with melasma and 68-73% of patients improved.Yes.
Liquorice extract/Licorice extractGlabridinInhibits tyrosinase activity (similar to kojic acid).A combination product of 0.4% licorice extract, 0.05% betamethasone, and 0.05% retinoic acid was found to be effective in the treatment of melasma.Yes.
HydroquinoneAn industrial chemicalInhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes. Also competes for tyrosine oxidation in active melanocytes.One of the most effective inhibitors of melanogenesis in vitro and in vivo. Evidence of improvement is usually observed at 4-6 weeks. Tretinoin has been used to enhance the efficacy of hydroquinone.Mostly safe, but risks exist.

Exogenous ochronosis observed in black patients who have used high concentrations for years.
Thus, it should be discontinued if no improvement occurs within 4-6 months.
Mulberry extractDerived from root of paper mulberry plant (Morus alba root).Inhibits tyrosinase activity.Low concentrations shown to inhibit tyrosinase activity. Significantly lower compared to the concentrations needed for kojic acid and hydroquinone.Yes.
Azelaic acidDerived from yeast.Inhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes.A 20% concentration of azelaic acid is equivalent to 2% hydroquinone. However, azelaic acid has no lightening effect on normally pigmented skin, freckles, senile lentigines, and nevi. It has selective effects on only abnormal melanocytes.Yes.
NiacinamideVitamin B3, niacin, nicotinamideInhibits melanosome transfer from melanocytes to keratinocytes.In skin culture tests, niacinamide significantly inhibited the transfer of melanosomes from melanocytes to keratinocytes (by 25–45%; p activity.Yes.
Salicylic acidA beta hydroxy acid (BHA) used to make aspirin.Increases cell turnover.Effective on minor skin discolorations.Yes, in lower concentrations only.
Undecylenoyl phenylalanineAmino acid derivative. Commercial names include Skinwhite MSH and Sepiwhite MSH.Acts as an antagonist to melanocyte stimulating hormone (MSH). Prevents the start of melanin synthesis.In testing, melanin levels were significantly reduced by 53% after 13 days.Yes.
Topical corticosteroidsSeveral forms of corticosteroids include Hydrocortisone,
Clobetasol Propionate, Fluocinolone Acetonide or Betamethasone Dipropionate.
Unknown. It is possible that steroids reduce the production of melanocyte stimulating hormones (MSH).Fast temporary skin lightening, but prolonged use is dangerous.No.
MonobenzoneMonobenzyl ether of hydroquinonePermanently depigments normal skin.Used for vitiligo patients.Used for vitiligo patients only.
MequinolMonomethyl ether of hydroquinoneCytotoxic to melanocytes.Can be effective when used in conjunction with tretinoin.Yes, in lower concentrations only.

@SubhumanCurrycel @Face is everything
 
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I found this and thought that it could be helpful for my ethnic looksmaxxers here. You can get most of them online&legal.
-->Ingredients with the red color are proven to work (if you believe youtubers before/after)



IngredientDescriptionHow it worksEfficacySafe on darker skin?
ArbutinA hydroquinone derivative (glycosylated benzoquinone) extracted from the bearberry shrub.Inhibits tyrosinase to prevent the formation of melanin.Arbutin found to inhibit melanin production in B16 cells induced with alpha-MSH and decreases tyrosinase activity. Less effective than kojic acid.Yes.
Alpha-ArbutinAlpha-Arbutin is an epimer of arbutin (4-hydroxyphenyl alpha-glucopyranoside)Inhibits tyrosinase to prevent the formation of melanin. Said to have a stronger effect than arbutin.Melanin synthesis was reduced to 40% with 250 microg of alpha-arbutin.Yes.
Magnesium ascorbyl phosphateA stable vitamin C derivativeSuppresses melanin formation and protects against skin damage caused by UVB rays.A significant lightening effect was seen clinically in 19 of 34 patients with melasma and solar lentigos.Yes.
Kojic acidDerived from fungusSuppresses tyrosinase activity.Less efficacious than 2% hydroquinone.

May cause contact dermatitis and erythema.
Yes.
Retin A/
Tretinoin
Retinoic acid/Vitamin A acidBoosts epidermal turnover, which promotes keratinocyte proliferation. Discharges epidermal melanin but not dermal melanin.Tretinoin was used as monotherapy in a study on 38 African- American patients with melasma and 68-73% of patients improved.Yes.
Liquorice extract/Licorice extractGlabridinInhibits tyrosinase activity (similar to kojic acid).A combination product of 0.4% licorice extract, 0.05% betamethasone, and 0.05% retinoic acid was found to be effective in the treatment of melasma.Yes.
HydroquinoneAn industrial chemicalInhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes. Also competes for tyrosine oxidation in active melanocytes.One of the most effective inhibitors of melanogenesis in vitro and in vivo. Evidence of improvement is usually observed at 4-6 weeks. Tretinoin has been used to enhance the efficacy of hydroquinone.Mostly safe, but risks exist.

Exogenous ochronosis observed in black patients who have used high concentrations for years.
Thus, it should be discontinued if no improvement occurs within 4-6 months.
Mulberry extractDerived from root of paper mulberry plant (Morus alba root).Inhibits tyrosinase activity.Low concentrations shown to inhibit tyrosinase activity. Significantly lower compared to the concentrations needed for kojic acid and hydroquinone.Yes.
Azelaic acidDerived from yeast.Inhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes.A 20% concentration of azelaic acid is equivalent to 2% hydroquinone. However, azelaic acid has no lightening effect on normally pigmented skin, freckles, senile lentigines, and nevi. It has selective effects on only abnormal melanocytes.Yes.
NiacinamideVitamin B3, niacin, nicotinamideInhibits melanosome transfer from melanocytes to keratinocytes.In skin culture tests, niacinamide significantly inhibited the transfer of melanosomes from melanocytes to keratinocytes (by 25–45%; p activity.Yes.
Salicylic acidA beta hydroxy acid (BHA) used to make aspirin.Increases cell turnover.Effective on minor skin discolorations.Yes, in lower concentrations only.
Undecylenoyl phenylalanineAmino acid derivative. Commercial names include Skinwhite MSH and Sepiwhite MSH.Acts as an antagonist to melanocyte stimulating hormone (MSH). Prevents the start of melanin synthesis.In testing, melanin levels were significantly reduced by 53% after 13 days.Yes.
Topical corticosteroidsSeveral forms of corticosteroids include Hydrocortisone,
Clobetasol Propionate, Fluocinolone Acetonide or Betamethasone Dipropionate.
Unknown. It is possible that steroids reduce the production of melanocyte stimulating hormones (MSH).Fast temporary skin lightening, but prolonged use is dangerous.No.
MonobenzoneMonobenzyl ether of hydroquinonePermanently depigments normal skin.Used for vitiligo patients.Used for vitiligo patients only.
MequinolMonomethyl ether of hydroquinoneCytotoxic to melanocytes.Can be effective when used in conjunction with tretinoin.Yes, in lower concentrations only.

@SubhumanCurrycel @Face is everything
Great thread mirin effort
 
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how much of a difference does it even make in skin color...not that i'm thinking of using it
 
I found this and thought that it could be helpful for my ethnic looksmaxxers here. You can get most of them online&legal.
-->Ingredients with the red color are proven to work (if you believe youtubers before/after)



IngredientDescriptionHow it worksEfficacySafe on darker skin?
ArbutinA hydroquinone derivative (glycosylated benzoquinone) extracted from the bearberry shrub.Inhibits tyrosinase to prevent the formation of melanin.Arbutin found to inhibit melanin production in B16 cells induced with alpha-MSH and decreases tyrosinase activity. Less effective than kojic acid.Yes.
Alpha-ArbutinAlpha-Arbutin is an epimer of arbutin (4-hydroxyphenyl alpha-glucopyranoside)Inhibits tyrosinase to prevent the formation of melanin. Said to have a stronger effect than arbutin.Melanin synthesis was reduced to 40% with 250 microg of alpha-arbutin.Yes.
Magnesium ascorbyl phosphateA stable vitamin C derivativeSuppresses melanin formation and protects against skin damage caused by UVB rays.A significant lightening effect was seen clinically in 19 of 34 patients with melasma and solar lentigos.Yes.
Kojic acidDerived from fungusSuppresses tyrosinase activity.Less efficacious than 2% hydroquinone.

May cause contact dermatitis and erythema.
Yes.
Retin A/
Tretinoin
Retinoic acid/Vitamin A acidBoosts epidermal turnover, which promotes keratinocyte proliferation. Discharges epidermal melanin but not dermal melanin.Tretinoin was used as monotherapy in a study on 38 African- American patients with melasma and 68-73% of patients improved.Yes.
Liquorice extract/Licorice extractGlabridinInhibits tyrosinase activity (similar to kojic acid).A combination product of 0.4% licorice extract, 0.05% betamethasone, and 0.05% retinoic acid was found to be effective in the treatment of melasma.Yes.
HydroquinoneAn industrial chemicalInhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes. Also competes for tyrosine oxidation in active melanocytes.One of the most effective inhibitors of melanogenesis in vitro and in vivo. Evidence of improvement is usually observed at 4-6 weeks. Tretinoin has been used to enhance the efficacy of hydroquinone.Mostly safe, but risks exist.

Exogenous ochronosis observed in black patients who have used high concentrations for years.
Thus, it should be discontinued if no improvement occurs within 4-6 months.
Mulberry extractDerived from root of paper mulberry plant (Morus alba root).Inhibits tyrosinase activity.Low concentrations shown to inhibit tyrosinase activity. Significantly lower compared to the concentrations needed for kojic acid and hydroquinone.Yes.
Azelaic acidDerived from yeast.Inhibits DNA synthesis and mitochondrial enzymes, has direct cytotoxic effects toward melanocytes.A 20% concentration of azelaic acid is equivalent to 2% hydroquinone. However, azelaic acid has no lightening effect on normally pigmented skin, freckles, senile lentigines, and nevi. It has selective effects on only abnormal melanocytes.Yes.
NiacinamideVitamin B3, niacin, nicotinamideInhibits melanosome transfer from melanocytes to keratinocytes.In skin culture tests, niacinamide significantly inhibited the transfer of melanosomes from melanocytes to keratinocytes (by 25–45%; p activity.Yes.
Salicylic acidA beta hydroxy acid (BHA) used to make aspirin.Increases cell turnover.Effective on minor skin discolorations.Yes, in lower concentrations only.
Undecylenoyl phenylalanineAmino acid derivative. Commercial names include Skinwhite MSH and Sepiwhite MSH.Acts as an antagonist to melanocyte stimulating hormone (MSH). Prevents the start of melanin synthesis.In testing, melanin levels were significantly reduced by 53% after 13 days.Yes.
Topical corticosteroidsSeveral forms of corticosteroids include Hydrocortisone,
Clobetasol Propionate, Fluocinolone Acetonide or Betamethasone Dipropionate.
Unknown. It is possible that steroids reduce the production of melanocyte stimulating hormones (MSH).Fast temporary skin lightening, but prolonged use is dangerous.No.
MonobenzoneMonobenzyl ether of hydroquinonePermanently depigments normal skin.Used for vitiligo patients.Used for vitiligo patients only.
MequinolMonomethyl ether of hydroquinoneCytotoxic to melanocytes.Can be effective when used in conjunction with tretinoin.Yes, in lower concentrations only.

@SubhumanCurrycel @Face is everything
lmfao fucking mental asylum why would u want to whiten your skin that much
 
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Dont waste time and money. Just dont go outside thats the only way
 
Hey @hopolessmofoker
I have alpha arbutine %2 + HA . How should i use this product? How many of a week ?
My skin looks like curry :lul: but not too much. I will use for more whitening
 
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Hey @hopolessmofoker
I have alpha arbutine %2 + HA . How should i use this product? How many of a week ?
My skin looks like curry :lul: but not too much. I will use for more whitening
on the Website they say u can use it 2x daily, am and pm. but you should combine it with some sort of vitamin C and retinol or chemical Peeling (not daily)
 
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on the Website they say u can use it 2x daily, am and pm. but you should combine it with some sort of vitamin C and retinol or chemical Peeling (not daily)
Did you whiten your skin.
 
Where did u find this from?

post link bro
 
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BEST thread on .org hands down

Every curry should be required to read this before they sign up
jfl
 
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