The absolute efficacy of my bonestack is unparalleled

How long have you been on it? I have loox bone stack if you haven’t seen it I’ll send it.
Havent tried it yet and I have seen loox stack, but I forgot exactly what was in it.

Send it tbh
 
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@Bitchwhipper2 how will the stack work if there is no mechanical tension on the bone ?
 
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Show a study that says this
“We also showed a 4‑fold increase in bone formation rate on the periosteal surface, suggesting that hPTH(1‑34) has the potential to increase bone diameter in humans.”


The effect on the periosteum relative to endocortical and tracebular is actually elevated in pth compared to baseline.

If anything its SELECTIVE for facial bone
 
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@Bitchwhipper2 how will the stack work if there is no mechanical tension on the bone ?
Mechanichal tension is not required for growth.

This should be obvious looking at cranial enlargement in acromegalics
 
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Hgh, test, var, teriparatide, vorinostat and mk4 (I think)
That's a molecule compared to what I will be running :feelswhat:

Me and @Bitchwhipper2 are the ultimate gatekeeping forum brothers :cool:
 
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Mogs loox mumbai tier combination of chemicals to dirt

This is human advancement at its finest
bragging and gatekeeping just k/ys nobody gaf fuck you
 
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If you're taking Teriparatide I'm assuming you're taking Denosumab alongside it. Ignore the rest of this comment if you aren't, but Denosumab and Teriparatide are unlikely to grow facial bones because they primarily affect trabecular bone, which is abundant in the spine and hips but not so much in the cortical dense bones of the face (the mandible, maxilla, zygos, etc). After puberty, facial bones undergo very limited remodeling, there are few active sites for these drugs to work on. Teriparatide stimulates bone formation only where remodeling is already occurring, and Denosumab suppresses remodeling by inhibiting osteoclasts which further reduces the potential for actual note worthy structural changes. While both drugs synergizing together can increase bone density in weight bearing areas, it does not reshape or enlarge bones, especially not in the craniofacial region. I nearly fell victim to this as well, but just looking through studies on the two they're nearly all examining the spine or hips which are just so structurally different from any craniofacial bones
So what should I be taking for facial bone mass? Stack recommendations?
 
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So what should I be taking for facial bone mass? Stack recommendations?
Hes wrong btw
denosumab is trash btw and I can go in to exact details given enough shekels

And Teriparatide still shows abundant activity at the periosteum.

Iirc the reason its said that "pth doesnt grow facial bones" is because when growing facial bones, what youre doing is expanding the periosteum.

PTH works best when theres osteoclast activity, but the periosteum has an osteoblast-osteoclast ratio of 10-1, so im theory its shit for this purpose.

But what we do see is the exact opposite.

"eatment with PTH … significantly increased periosteal MS/BS (+43%), MAR (+690%), and BFR/BS (+540%) … these findings confirm that ABL and PTH significantly increased cortical thickness … increasing periosteal apposition"
 
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oh alright, does age matter if your taking it in puberty anyways? I won’t be able to cycle till I’m 16-18
Youll get more results the younger you are. But facial growth can occur at any age
 
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Youll get more results the younger you are. But facial growth can occur at any age
holy shit bet, what about maxillary ressession??? Can it fix?
 
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holy shit bet, what about maxillary ressession??? Can it fix?
From what I know, no. Remodeling is not the same as bone growth.
I dont believe you can change the shape of adult bone. Only grow the size

With that said I have done no research on remodling. Everything Ive learned is in terms of bone thickening.

But I will likely look in to it in the future. Most likely candidates for remodeling would be T3 + pth + HDACi or anything kind of epigenetic tool
 
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From what I know, no. Remodeling is not the same as bone growth.
I dont believe you can change the shape of adult bone. Only grow the size

With that said I have done no research on remodling. Everything Ive learned is in terms of bone thickening.

But I will likely look in to it in the future. Most likely candidates for remodeling would be T3 + pth + HDACi or anything kind of epigenetic tool
You think it would be able to remodel if you used something like a face mask with the compounds? Or thumbpull??
 
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You think it would be able to remodel if you used something like a face mask with the compounds? Or thumbpull??
From what I know, the sutures are closed after like 12.

Maxillar is the one part of the face I genuinely cant help you with/lack any sort of theories about.

Jaw is easy, zygos is easy, browridge is easy. Maxilla... Idk. Maybe. Its possible that the sutures remain slightly open and using t3 + teriparatide + hgh could supercharge the remodeling process while you apply some kind of force stimulus
 
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From what I know, the sutures are closed after like 12.

Maxillar is the one part of the face I genuinely cant help you with/lack any sort of theories about.

Jaw is easy, zygos is easy, browridge is easy. Maxilla... Idk. Maybe. Its possible that the sutures remain slightly open and using t3 + teriparatide + hgh could supercharge the remodeling process while you apply some kind of force stimulus
Sutures close at 14-16 is what everyone’s saying, so either use the compounds and try to move your maxilla or use compounds for bones first then get surgery for your maxilla? How much is the full stack?
 
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Sutures close at 14-16 is what everyone’s saying, so either use the compounds and try to move your maxilla or use compounds for bones first then get surgery for your maxilla? How much is the full stack?
You dont wanna use the full stack if you wanna target remodeling.
It would probably benefit you more than baseline, but it has some anti resorbative agents making it unideal for remodeling.

If you want pure remodeling you want osteoblasts AND osteoclasts as high as possible while using force stimulus. For pure growth you only need osteoblasts.
 
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You dont wanna use the full stack if you wanna target remodeling.
It would probably benefit you more than baseline, but it has some anti resorbative agents making it unideal for remodeling.

If you want pure remodeling you want osteoblasts AND osteoclasts as high as possible while using force stimulus. For pure growth you only need osteoblasts.
So how do you target osteoblasts? And do you can’t have bone remodeling+bone mass increase at the same time?
 
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So how do you target osteoblasts? And do you can’t have bone remodeling+bone mass increase at the same time?
Yes you can have both. But to maximise one you cant maximise the other.

I have said my part now. Good luck kid
 
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Yes you can have both. But to maximise one you cant maximise the other.

I have said my part now. Good luck kid
I have one more question, so would I remodeling stack look like this?
IMG 6859
 
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Yes, that looks good.

But really do your research on t3.

Amazing compound, but can fuck you over if used incorrectly. All im saying
Alright, thanks
 
denosumab is trash btw and I can go in to exact details given enough shekels

And Teriparatide still shows abundant activity at the periosteum.

Iirc the reason its said that "pth doesnt grow facial bones" is because when growing facial bones, what youre doing is expanding the periosteum.

PTH works best when theres osteoclast activity, but the periosteum has an osteoblast-osteoclast ratio of 10-1, so im theory its shit for this purpose.

But what we do see is the exact opposite.

"eatment with PTH … significantly increased periosteal MS/BS (+43%), MAR (+690%), and BFR/BS (+540%) … these findings confirm that ABL and PTH significantly increased cortical thickness … increasing periosteal apposition"
Interesting, I actually didn't know any of that. I'll have to look into it some more but you seem like you know what you're doing :Comfy:
 
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So what should I be taking for facial bone mass? Stack recommendations?
Not sure if I'm being honest. I don't bother researching drugs that "grow bone" since mostly everything people on here claim either has negligible effects on craniofacial development or is straight up incorrect
 
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