Zinc, Azelaic acid and B6 as a possible and cheap 5-alpha-reductase inhibitor

[Unhuman]

Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid - PubMed

The effects of zinc sulphate and azelaic acid on 5 alpha-reductase activity in human skin were studied using an in vitro assay with 1,2[3H]-testosterone as substrate. When added at concentrations of 3 or 9 mmol/l, zinc was a potent inhibitor of 5 alpha-reductase activity. At high concentrations...

pubmed.ncbi.nlm.nih.gov

The effects of zinc sulphate and azelaic acid on 5 alpha-reductase activity in human skin were studied using an in vitro assay with 1,2[3H]-testosterone as substrate. When added at concentrations of 3 or 9 mmol/l, zinc was a potent inhibitor of 5 alpha-reductase activity. At high concentrations, zinc could completely inhibit the enzyme activity. Azelaic acid was also a potent inhibitor of 5 alpha-reductase; inhibition was detectable at concentrations as low as 0.2 mmol/l and was complete at 3 mmol/l. An additive effect of the two inhibitors was observed. Vitamin B6 potentiated the inhibitory effect of zinc, but not of azelaic acid, suggesting that two different mechanisms are involved. When the three substances were added together at very low concentrations which had been shown to be ineffective alone, 90% inhibition of 5 alpha-reductase activity was obtained. If this inhibition is confirmed in vivo, zinc sulphate combined with azelaic acid could be an effective agent in the treatment of androgen related pathology of human skin.

HIGH IQ thread coming soon.

 

[Moggie]

jfl 5mg fin is probs cheaper than any of these

 

[Unhuman]

jfl 5mg fin is probs cheaper than any of these

Are you talking about pills that you need to quarter in order to get a standard dose? Also would you be able to post sources that ship to the EU?

 

[Moggie]

Are you talking about pills that you need to quarter in order to get a standard dose? Also would you be able to post sources that ship to the EU?

yeah, cant you just get it prescribed by a doc?

 

[Unhuman]

yeah, cant you just get it prescribed by a doc?

Im from the UK. It takes ages to get an appointment.

 

[incel194012940]

but zinc make me cum load and cum make me lose hair

 

[Hero of the Imperium]

i want to increase Dht