
Copercel
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Wdym by Skinmaxxing is cope??great skin, but this show very well how much of a cope skinmaxxing really is. if anything, you just look gay to the untrained eye.
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Wdym by Skinmaxxing is cope??great skin, but this show very well how much of a cope skinmaxxing really is. if anything, you just look gay to the untrained eye.
For my motive:
Here's a clear cost comparison between Red Light Therapy (RLT) and GHK-Cu injections, over time:
1. Red Light Therapy (RLT) — One-time investment, minimal upkeep
Item Approximate Cost High-quality RLT panel (like Hooga, PlatinumLED, Mito, etc.) $200–$600 (once) Lifespan 5–10 years Daily use cost $0 (just electricity, negligible) Supporting nutrients (vitamin C, glycine, collagen, copper) ~$20–40/month (if not already in diet)
Monthly cost over 3 years:
2. GHK-Cu Injections — High, recurring costs
Item Approximate Cost GHK-Cu peptide (injectable) $100–$250/month (depending on source & dose) Syringes, alcohol wipes ~$10/month Possible doctor visits (if supervised) $0–$100 extra Nutrients (if taken with injections) ~$20–40/month
Monthly cost:
Cost Comparison Summary
Feature RLT GHK-Cu Injections Upfront cost Medium Low Ongoing cost Very low High recurring 3-year cost estimate ~$200–$600 total $4,000–$9,000 total Cost-efficiency Excellent
Expensive long-term
Verdict:
(Glycin, Copper and Vitamin C are cheap as fuck btw)
Are u trying to say that i am coping ?
Tretinoin glow is ugly as fuck for realgreat skin, but this show very well how much of a cope skinmaxxing really is. if anything, you just look gay to the untrained eye.
He’s saying you’re using gpt.Are u trying to say that i am coping ?
glow skin is such a looksmin.Tretinoin glow is ugly as fuck for real
I use Perplexity habitually but i was lazy I am sorryHe’s saying you’re using gpt.
glow skin is such a looksmin.
make this a threadFor my motive:
Here's a clear cost comparison between Red Light Therapy (RLT) and GHK-Cu injections, over time:
1. Red Light Therapy (RLT) — One-time investment, minimal upkeep
Item Approximate Cost High-quality RLT panel (like Hooga, PlatinumLED, Mito, etc.) $200–$600 (once) Lifespan 5–10 years Daily use cost $0 (just electricity, negligible) Supporting nutrients (vitamin C, glycine, collagen, copper) ~$20–40/month (if not already in diet)
Monthly cost over 3 years:
2. GHK-Cu Injections — High, recurring costs
Item Approximate Cost GHK-Cu peptide (injectable) $100–$250/month (depending on source & dose) Syringes, alcohol wipes ~$10/month Possible doctor visits (if supervised) $0–$100 extra Nutrients (if taken with injections) ~$20–40/month
Monthly cost:
Cost Comparison Summary
Feature RLT GHK-Cu Injections Upfront cost Medium Low Ongoing cost Very low High recurring 3-year cost estimate ~$200–$600 total $4,000–$9,000 total Cost-efficiency Excellent
Expensive long-term
Verdict:
(Glycin, Copper and Vitamin C are cheap as fuck btw)
It’s chat GPT if you didn’t notice.make this a thread
yeah its gpt made but its facts right red light therapy is better and its just one time. Ima do itIt’s chat GPT if you didn’t notice.
Great thread OP, even tho I doubt you will even see this.
GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently so than its supposed benefits².
![]()
Quickly, Glycyl-L-histidyl-L-lysine (GHK) is a tripeptide isolated from human plasma³, which possesses a high affinity for copper (II) ions, with which it spontaneously forms a complex (GHK-Cu). GHK alone has been shown to be responsible for the collagen boost⁴ and no injection-related pain has been reported with it⁵, so go for it if you want but it's the added copper that is responsible for this myriad of blessings;
EXAMPLES :
The complex, unlike GHK alone, helps activate matrix metalloproteinases, which break down damaged tissue so it can be replaced with healthy tissue⁶.
View attachment 3275853
OR
Compositions of copper (II) containing compounds have been show to accelerate the healing of wounds in warm-blooded animals, and more specifically the systemic loading of copper (II) compounds to accelerate the rate of wound healing following injury or surgery to warm-blooded animals.⁷
View attachment 3275859
; ...and consequently what seems to cause tissue damage during injection.
If we look at the cayman chemicals reviews of the molecules in question :
View attachment 3275820View attachment 3275821
The main differences are the addition of a copper atom and a significantly worse solubility profile, which suggests a causal relationship between these two differences (meaning that the added copper induces the worse solubility).
In fact, we know that metals are gay
Gay meaning they have different bonding properties vs carbon, oxygen, etc (this whole field of gay metals is “inorganic chemistry”) The reason for this is that metals basically have up to ten relevant electrons , which have comically complex geometries, are much larger (radius) and less bound to the nucelus
View attachment 3275870
Simply, they like to move a lot, they're playful building blocks that like to change and mix, while other atoms are stronger and stick together better,
other atoms, like those in water or air, are like super strong blocks that hold together really well
. They don’t like to change as much, so they are usually more stable.
Seriously, metals require ions to stabilize in various contexts, primarily due to their tendency to lose electrons and form positive charges, the ions in PBS can neutralize the positive charge of the copper ions, reducing the likelihood of oxidation or other reactions that would destabilize the copper. PBS also maintains a stable pH, which is important for keeping copper in its soluble form. In bac water or regular saline, changes in pH can lead to precipitation or oxidation of copper ions. (5 to 7 for bac and reg saline vs 7.2 to 7.4 for Phosphate Buffered Saline)
Hence why GHK-Cu needs PBS (again because the ionic solution (has a lot of ions) stabilizes the added copper), otherwise the copper-nitrogen bonds are likely to break.
View attachment 3276079
The common folk seems to be dissolving GHK-Cu in Bac Water since that is the usual commercially available and promoted solvent for peptides².
However, Bac Water has a lower ion concentration than PBS (which makes the copper less likely to be stable), I hypothesize that the pain comes from the free copper atoms raping your tissues (not fully understood).
View attachment 3275864
Injection solutions :
Phosphate Buffered Saline :
View attachment 3275998
View attachment 3276003
View attachment 3276026
i.e. what is mostly used in studies and what is recommended by CaymanChem
Making PBS at home looks annoying af so just fucking buy it : https://www.sigmaaldrich.com/US/en/product/sigma/d8537
WORKS AND STABLE
Normale saline (0.9% saline) :
Direct on-site injection tho
View attachment 3276031
View attachment 3276018View attachment 3276019
WORKS BUT THEORETICALLY NOT STABLE, since the PH will be too low
You'd need to adjsut it yourself⁷
View attachment 3276064
BAC WATER :
DOESN'T WORK (YOU ONLY GET GHK AND INJECTION SITE DAMAGE)²
Topical :
Topical formulations of GHKcu have been developed and are effective
BetTar:
The best one (both low-cost, most effective and most stable) being Bet Tar which is a recent (2023) chinese developped ionic-liquid-based delivery vehicle composed of betaine and tartaric acid
![]()
View attachment 3276085
View attachment 3276086
View attachment 3276090
Stable as fuck :
View attachment 3276087
PDI is dispersity
I will be attaching the papers⁸ in case President Xi takes them down
Hyaluronic acid-based hydrogel embedded with GHK peptide nanofibers : ()
Works af for direct wound healing
View attachment 3276113
YES BRO I WILL TOTALLY MAKE THIS jfl
View attachment 3276114
THERE ARE 8 BILLION GOOD TOPICAL ways but WE CAN NOT MAKE/BUY any of these
This was good for wound closure but go figure how they made it
View attachment 3276058View attachment 3276117
Concering DMSO :
IT DOESN'T WORK (IT'S EVEN LESS STABLE THAN BAC WATER since it has less ions (water (bac water) has H+ and OH- (water)))
These niggas tried to study its structure while dissolving it in DMSO¹⁰ : https://sci-hub.ru/10.1016/0162-0134(89)84011-5, which gave them completly retarded results "under their conditions"
Metals in general seem to be struggling in DMSO
View attachment 3276159
Goodluck rabbitholemaxxing this
TLDR :
- RECONSTITUTE GHK-Cu IN PBS or DPBS (which you can buy) and inject it daily
- BUY and RECONSTITUTE GHK IN BAC WATER IF YOU ONLY WANT COLLAGEN BOOST AND EASE OF USE and inject it daily
- TRY TO MAKE a [Bet] [Tar] GHK-Cu Topical Liquid Solution, if you want, for when you can't inject or as first-aid
@Hexmask @N1666 @Clavicular @NorwoodAscender @meathead
¹Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/pdf/ijms-19-01987.pdf
²
³Pickart L, Thaler MM. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver. Nat New Biol. 1973 May 16;243(124):85-7. PMID: 4349963.
⁴Maquart, F.-X., Pickart, L., Laurent, M., Gillery, P., Monboisse, J.-C., & Borel, J.-P. (1988). Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺. Biochemical and Biophysical Research Communications, 238(2), 343-346. https://sci-hub.ru/10.1016/0014-5793(88)80509-X
⁵ Google it and add Reddit and various forums to the key-words
⁶Siméon, A., Emonard, H., Hornebeck, W., & Maquart, F.-X. (2000). The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sciences, 67(20), 2257-2265. https://sci-hub.ru/10.1016/S0024-3205(00)00803-1
⁷ Pickart, L. R. (1992). Method of using copper(II) containing compounds to accelerate wound healing (U.S. Patent No. 5164367). U.S. Patent and Trademark Office. https://patentimages.storage.googleapis.com/28/c1/c7/6fb3bbcf61becb/US5164367.pdf
⁸Liu, T., Hu, L., Lu, B., Bo, Y., Liao, Y., Zhan, J., Pei, Y., Sun, H., Wang, Z., Guo, C., & Zhang, J. (2023). A novel delivery vehicle for copper peptides. New Journal of Chemistry https://pubs.rsc.org/en/content/articlelanding/2023/nj/d2nj04282g#fn1
⁹L. Pickart, in BioIogy of Copper Complexes, J. R. C. Sorenson, Ed., Human Press, Clifton, NJ, 1987, pp. 273-285 (https://library.lol/main/04A4B0236383B58B30E1AF569542355F), neurogenesis also mentionned here¹⁰
¹⁰Antholine, W. E., Petering, D. H., & Pickart, L. (1989). ESR studies of the interaction of copper(II) GHK, histidine, and Ehrlich cells. Journal of Inorganic Biochemistry, 35(2), U-224
¹¹Pickart, L., Vasquez-Soltero, J. M., & Margolina, A. (2012). The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: Implications for cognitive health. Oxidative Medicine and Cellular Longevity, 2012, Article ID 324832. https://doi.org/10.1155/2012/324832
GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently so than its supposed benefits².
![]()
Quickly, Glycyl-L-histidyl-L-lysine (GHK) is a tripeptide isolated from human plasma³, which possesses a high affinity for copper (II) ions, with which it spontaneously forms a complex (GHK-Cu). GHK alone has been shown to be responsible for the collagen boost⁴ and no injection-related pain has been reported with it⁵, so go for it if you want but it's the added copper that is responsible for this myriad of blessings;
EXAMPLES :
The complex, unlike GHK alone, helps activate matrix metalloproteinases, which break down damaged tissue so it can be replaced with healthy tissue⁶.
View attachment 3275853
OR
Compositions of copper (II) containing compounds have been show to accelerate the healing of wounds in warm-blooded animals, and more specifically the systemic loading of copper (II) compounds to accelerate the rate of wound healing following injury or surgery to warm-blooded animals.⁷
View attachment 3275859
; ...and consequently what seems to cause tissue damage during injection.
If we look at the cayman chemicals reviews of the molecules in question :
View attachment 3275820View attachment 3275821
The main differences are the addition of a copper atom and a significantly worse solubility profile, which suggests a causal relationship between these two differences (meaning that the added copper induces the worse solubility).
In fact, we know that metals are gay
Gay meaning they have different bonding properties vs carbon, oxygen, etc (this whole field of gay metals is “inorganic chemistry”) The reason for this is that metals basically have up to ten relevant electrons , which have comically complex geometries, are much larger (radius) and less bound to the nucelus
View attachment 3275870
Simply, they like to move a lot, they're playful building blocks that like to change and mix, while other atoms are stronger and stick together better,
other atoms, like those in water or air, are like super strong blocks that hold together really well
. They don’t like to change as much, so they are usually more stable.
Seriously, metals require ions to stabilize in various contexts, primarily due to their tendency to lose electrons and form positive charges, the ions in PBS can neutralize the positive charge of the copper ions, reducing the likelihood of oxidation or other reactions that would destabilize the copper. PBS also maintains a stable pH, which is important for keeping copper in its soluble form. In bac water or regular saline, changes in pH can lead to precipitation or oxidation of copper ions. (5 to 7 for bac and reg saline vs 7.2 to 7.4 for Phosphate Buffered Saline)
Hence why GHK-Cu needs PBS (again because the ionic solution (has a lot of ions) stabilizes the added copper), otherwise the copper-nitrogen bonds are likely to break.
View attachment 3276079
The common folk seems to be dissolving GHK-Cu in Bac Water since that is the usual commercially available and promoted solvent for peptides².
However, Bac Water has a lower ion concentration than PBS (which makes the copper less likely to be stable), I hypothesize that the pain comes from the free copper atoms raping your tissues (not fully understood).
View attachment 3275864
Injection solutions :
Phosphate Buffered Saline :
View attachment 3275998
View attachment 3276003
View attachment 3276026
i.e. what is mostly used in studies and what is recommended by CaymanChem
Making PBS at home looks annoying af so just fucking buy it : https://www.sigmaaldrich.com/US/en/product/sigma/d8537
WORKS AND STABLE
Normale saline (0.9% saline) :
Direct on-site injection tho
View attachment 3276031
View attachment 3276018View attachment 3276019
WORKS BUT THEORETICALLY NOT STABLE, since the PH will be too low
You'd need to adjsut it yourself⁷
View attachment 3276064
BAC WATER :
DOESN'T WORK (YOU ONLY GET GHK AND INJECTION SITE DAMAGE)²
Topical :
Topical formulations of GHKcu have been developed and are effective
BetTar:
The best one (both low-cost, most effective and most stable) being Bet Tar which is a recent (2023) chinese developped ionic-liquid-based delivery vehicle composed of betaine and tartaric acid
![]()
View attachment 3276085
View attachment 3276086
View attachment 3276090
Stable as fuck :
View attachment 3276087
PDI is dispersity
I will be attaching the papers⁸ in case President Xi takes them down
Hyaluronic acid-based hydrogel embedded with GHK peptide nanofibers : ()
Works af for direct wound healing
View attachment 3276113
YES BRO I WILL TOTALLY MAKE THIS jfl
View attachment 3276114
THERE ARE 8 BILLION GOOD TOPICAL ways but WE CAN NOT MAKE/BUY any of these
This was good for wound closure but go figure how they made it
View attachment 3276058View attachment 3276117
Concering DMSO :
IT DOESN'T WORK (IT'S EVEN LESS STABLE THAN BAC WATER since it has less ions (water (bac water) has H+ and OH- (water)))
These niggas tried to study its structure while dissolving it in DMSO¹⁰ : https://sci-hub.ru/10.1016/0162-0134(89)84011-5, which gave them completly retarded results "under their conditions"
Metals in general seem to be struggling in DMSO
View attachment 3276159
Goodluck rabbitholemaxxing this
TLDR :
- RECONSTITUTE GHK-Cu IN PBS or DPBS (which you can buy) and inject it daily
- BUY and RECONSTITUTE GHK IN BAC WATER IF YOU ONLY WANT COLLAGEN BOOST AND EASE OF USE and inject it daily
- TRY TO MAKE a [Bet] [Tar] GHK-Cu Topical Liquid Solution, if you want, for when you can't inject or as first-aid
@Hexmask @N1666 @Clavicular @NorwoodAscender @meathead
¹Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/pdf/ijms-19-01987.pdf
²
³Pickart L, Thaler MM. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver. Nat New Biol. 1973 May 16;243(124):85-7. PMID: 4349963.
⁴Maquart, F.-X., Pickart, L., Laurent, M., Gillery, P., Monboisse, J.-C., & Borel, J.-P. (1988). Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺. Biochemical and Biophysical Research Communications, 238(2), 343-346. https://sci-hub.ru/10.1016/0014-5793(88)80509-X
⁵ Google it and add Reddit and various forums to the key-words
⁶Siméon, A., Emonard, H., Hornebeck, W., & Maquart, F.-X. (2000). The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sciences, 67(20), 2257-2265. https://sci-hub.ru/10.1016/S0024-3205(00)00803-1
⁷ Pickart, L. R. (1992). Method of using copper(II) containing compounds to accelerate wound healing (U.S. Patent No. 5164367). U.S. Patent and Trademark Office. https://patentimages.storage.googleapis.com/28/c1/c7/6fb3bbcf61becb/US5164367.pdf
⁸Liu, T., Hu, L., Lu, B., Bo, Y., Liao, Y., Zhan, J., Pei, Y., Sun, H., Wang, Z., Guo, C., & Zhang, J. (2023). A novel delivery vehicle for copper peptides. New Journal of Chemistry https://pubs.rsc.org/en/content/articlelanding/2023/nj/d2nj04282g#fn1
⁹L. Pickart, in BioIogy of Copper Complexes, J. R. C. Sorenson, Ed., Human Press, Clifton, NJ, 1987, pp. 273-285 (https://library.lol/main/04A4B0236383B58B30E1AF569542355F), neurogenesis also mentionned here¹⁰
¹⁰Antholine, W. E., Petering, D. H., & Pickart, L. (1989). ESR studies of the interaction of copper(II) GHK, histidine, and Ehrlich cells. Journal of Inorganic Biochemistry, 35(2), U-224
¹¹Pickart, L., Vasquez-Soltero, J. M., & Margolina, A. (2012). The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: Implications for cognitive health. Oxidative Medicine and Cellular Longevity, 2012, Article ID 324832. https://doi.org/10.1155/2012/324832
How brahAnd ghkcu totally kills your IGF1 which is unfortunate
Nothing, do itwtf is stopping me from just buying a GHK-CU concentrated powder and then dissolving 200mg in sterile water and keeping in tbe
fridge?
i mean reconstituting it and then transferring it into a dropper bottle and applying topicallyNothing, do it
Isn’t GHK-Cu beneficial only when injected directly on site?RECONSTITUTE GHK-Cu IN PBS or DPBS (which you can buy) and inject it daily
NoIsn’t GHK-Cu beneficial only when injected directly on site?
Meaning, if you want facial collagen boost, you should inject in face (not great)
I do it with PBS for now, thinking about switching to bac.Thoughts on the pbs only theorem.
I think its meme tbh
Have you gotten any sort of pain using pbs?I do it with PBS for now, thinking about switching to bac.
Idk what’s better honestly atp
Very little PIP, not something unbearable.Have you gotten any sort of pain using pbs?
If you got pain using pbs it kindof destroys the free copper ions theorem aswell tbhVery little PIP, not something unbearable.
Also I’m still a teen, I don’t need to max GHK-ch efffects out of it since my collagen is already fine, so I will be switching to bac soon since it’s easier for me to get.Have you gotten any sort of pain using pbs?
You planning on using any retinoids in the future?Also I’m still a teen, I don’t need to max GHK-ch efffects out of it since my collagen is already fine, so I will be switching to bac soon since it’s easier for me to get.
Yes, the thread Jonas made is kinda theoreticalIf you got pain using pbs it kindof destroys the free copper ions theorem aswell tbh
But thanks. I just wanted a new line of evidence as I read a study outlining this:
"No detectable degradation at pH 5.5 and 7.4; stable at pH 4.5 as part of the broader range (pH 4.5–7.4)"
You used none of these chemicalsAlso I’m still a teen, I don’t need to max GHK-ch efffects out of it since my collagen is already fine, so I will be switching to bac soon since it’s easier for me to get.
I’m on Taz right nowYou planning on using any retinoids?
Theyre the most bang for your buck imo
Mirin, i wanna get back on taz. But everytime I try i get fucked cause already running accutaneI’m on Taz right now
Why would you try a topical retinoid and a oral one at the same time niggMirin, i wanna get back on taz. But everytime I try i get fucked cause already running accutane
Accutane in the beginning has no benefits to even negative effect on total collagen synthesis.Hey would you try a topical retinoid and a oral one at the same time nigg![]()
Both will rape you. Tbh cruising 15 mg accutane is great if your acne is mild-minimal, you don’t need ti add any topical retinoid.Accutane in the beginning has no benefits to even negative effect on total collagen synthesis.
What it does is help remodeling your skin in to a better structure though or something.
But id rather be using both than just one. Could quite possibly be synergistic
I cant roll with that pussy ass shit.Both will rape you. Tbh cruising 15 mg accutane is great if your acne is mild-minimal, you don’t need ti add any topical retinoid.
Your acne is bad?I cant roll with that pussy ass shit.
60mg or death
Not anymore, noYour acne is bad?
What dose are you on? Tbh just cruise it at 15-20 mg and do IPL laser to get that smooth skin look.
Wrong answer, for collagen & hair boost its topical only
60mg tbhWhat dose are you on? Tbh just cruise it at 15-20 mg
Thats expensive as fuck tbh.and do IPL laser to get that smooth skin look.
Wdym? Injectable GHK-cu is also for hair boost and collagenWrong answer, for collagen & hair boost its topical only
mirin60mg tbh
not really that expensive, you could get your own device with 100$Thats expensive as fuck tbh.
Could I not just dermastamp to fix the scarring or is ipl law
Bonestack takes first prio in the queue tbhmirin
not really that expensive, you could get your own device with 100$
Bonestack takes first prio in the queue tbh
Wdym? Injectable GHK-cu is also for hair boost and collagen
It's funny that you mention that because I debunked it in my thread you viewed exactly before posting this reply.If you got pain using pbs it kindof destroys the free copper ions theorem aswell tbh
But thanks. I just wanted a new line of evidence as I read a study outlining this:
"No detectable degradation at pH 5.5 and 7.4; stable at pH 4.5 as part of the broader range (pH 4.5–7.4)"
It's funny that you mention that because I debunked it in my thread you viewed exactly before posting this reply.
View attachment 3989055
@chadisbeingmade @imontheloose
Wasnt the premise that the low ph nuked the ions?It's funny that you mention that because I debunked it in my thread you viewed exactly before posting this reply.
View attachment 3989055
@chadisbeingmade @imontheloose