LifeFuel Possible drug to lighten eye colour? GTFIH

hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
goat2x said:
i dont even know tbh havent logged out since january
over
 
goat2x

goat2x

Gang Rapist furry freak cult leader
Joined
Jan 1, 2020
Posts
31,387
Reputation
77,911
Time online
312d 18h 46m
hairyballscel said:
 
T

TheEndHasNoEnd

No avi halo
Joined
Apr 9, 2020
Posts
6,707
Reputation
13,022
Time online
160d 14h 40m
Fuck this sucks to say but, even if you get this (which is rlly sucky because I found a cheap source from an actual lab), it won't do shit. Look at the abstract in that patent:

"To prevent permanent pigmentation of the iris caused by melanin deposit induced by pharmalogical treatments"
Ie the latanoprost in this case.
Look at this (brown eyes group):

This is the melanin production without latanoprost (which would theoretically be all of us). It actually increases the melanin production with metyrosine. Yet, it says the melanin content is lower with metyrosine in the no latanoprost. This clearly makes no sense, and it has to be a margin of error type of gain. The reason why is because of this (brown-blue eyes group):

Here it shows an increase of melanin content.

And here it shows an increase in melanin production similar to the brown eyes group.

You guys shouldnt be worried tho, because there's a surgery out there right now that targets the pigment in the eye and destroys it with a laser. It's completely harmless. Look up yeux Clair's.
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
TheEndHasNoEnd said:
Fuck this sucks to say but, even if you get this (which is rlly sucky because I found a cheap source from an actual lab), it won't do shit. Look at the abstract in that patent:
were not using that product, jfl i was never gonna use it, there are substances which inhibit melanin production significantly more without all these fucked side effects of metyrosine

and for brown blue eyes, yes it wont do as much, this would be mainly for going from dark brown to green/hazel
 
D

Deleted member 10987

Zephir
Joined
Nov 27, 2020
Posts
38,653
Reputation
49,044
Time online
91d 27m
Where do i buy it
 
D

Deleted member 10987

Zephir
Joined
Nov 27, 2020
Posts
38,653
Reputation
49,044
Time online
91d 27m
hairyballscel said:
dont

the drug is shit, i used it to prove a point
Why ?
I tought it lightened eyes ?
It doesnt work
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
Maesthetic said:
What side effect
  • Diarrhea
  • drooling
  • trembling and shaking of hands and fingers
  • trouble in speaking
  • Anxiety
  • confusion
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental depression
also ur not supposed to be driving or doing any hazardous activity as reactions could be impaired.
 
RecessedPrettyboy

RecessedPrettyboy

👁️
Joined
Oct 16, 2019
Posts
3,452
Reputation
5,214
Time online
195d 4h 4m
The only thing other than laser that will prob lighten your eyes is electrical stimulation/microcurrent
 
Deleted member 10949

Deleted member 10949

Fuck off
Joined
Nov 24, 2020
Posts
3,180
Reputation
3,727
Time online
37d 23h 30m
What if you stop taking the drug?
 
Deleted member 10949

Deleted member 10949

Fuck off
Joined
Nov 24, 2020
Posts
3,180
Reputation
3,727
Time online
37d 23h 30m
hairyballscel said:
You can also put it in your eye

there is a eye drop one
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
Nonstoplooksmax said:
You can also put it in your eye

there is a eye drop one
i was taking the piss
Nonstoplooksmax said:
What if you stop taking the drug?
pls read thru the tread

dont take the drug, its simply an example
 
D

Deleted member 1862

.
Joined
May 27, 2019
Posts
5,802
Reputation
9,439
Time online
76d 21h 14m
hairyballscel said:
i was taking the piss

pls read thru the tread

dont take the drug, its simply an example
is there smth better (let me cope)
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
aut0phobic said:
is there smth better (let me cope)
we have something, needs to be tested doe
 
Uglyandfat

Uglyandfat

4 PSL insecure narcy man
Joined
Jan 24, 2020
Posts
4,623
Reputation
5,324
Time online
43d 10h 58m
hairyballscel said:
Latanoprost is a medicine that treats high pressure inside the eye, it is a synthetic prostaglandin analogue, which as well as naturally occurring prostaglandins such as PGF2a and PGE2, have been shown to induce increased pigmentation in the iris. Here is some examples:

View attachment 601074 View attachment 601075

The way this works is still not completely clear, but for your eyes to get darker, increased synthesis of melanin must occur....

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1771317/
- https://www.sciencedirect.com/science/article/abs/pii/S0039625797800197
Melanin is derived from the amino acid—tyrosine—through a synthesis regulated by the enzyme tyrosinase. View attachment 601101


Tyrosinase is the most important enzyme in the synthesis of melanin, many skin lighteners work by inhibiting this enzyme. Tyrosinase inhibitors include hydroquinone arbutin, kojic acid, azelaic acid, L-ascorbic acid/Vitamin C. It no suprise that the aformentioned products are some of the best substances for lightening/treating hyperpigmentation.






Now this study claims that they have a drug which blocks the synthesis of tyrosinase, it works by using alpha-methyl-p-tyrosine


This study conducted an experiment to prove the effiacy of this drug in lightening BROWN EYES:
View attachment 601115
Now the arrow points to the amount of melanin content in the cells, we can see that use of alpha.-methyl-p-tyrosine decreases mealnin content in brown eyes, even without using latanoprost(the control), so this drug could possibly be used on its own to lighten dark eyes

It also decreased tyrinoase activity which is how skin lighteners often work

Except for one row, it consistently decreased melanin production, content and tyrosinase activity

"These results show that melanin production by iris melanocytes is inhibited by alpha.-methyl-p-tyrosine."


---------------------------------------------------------------------------
Results for brown-blue eyes


View attachment 601148
This is the second part of the study and it was conducted on blue-brown eyes, it still worked to inhibit melanin production, content and tyrosinase activity, but not as well as it did for brown eyes, as you can see, there a few rows melanin production increased, but this was probaly just random fluctuation, so this is probably more effective if you have very dark eyes.



"Although the present description concerns particularly the inhibition of melanin production induced by latanoprost, alpha.-methyl-p-tyrosine can be used successfully to inhibit the same Side effect of pigmentation induced by other pharmacological treatments or metabolic imbalance of different origin."

- This means that this drug doesn't have to be used in response to eye colour change from latanoprost, so it can be used without it

The name of the drug is metyrosine and for lightening the eyes it should be dosed at 100-500mg.


TLDR - metyrosine is a drug which significantly decreases melanin production, content and tyrosinase activity, those with high concentrations of melanin in the eyes have brown eyes, very little melanin makes eyes blue.



I could be wrong about all of this, seeing as there were no pics in the study, we don't know how this would translate visually, i want a discussion and wanna see ppls opinion on this





Cumskins when ethnics and blacks have blue and green eyes:

View attachment 601166
okay but I have light green eyes so delete this thread as it is not useful to me


jk
 
Deleted member 3043

Deleted member 3043

Life is about hapiness and i love you all.
Joined
Sep 3, 2019
Posts
36,684
Reputation
48,035
Time online
129d 16h 6m
Uglyandfat said:
okay but I have light green eyes so delete this thread as it is not useful to me


jk
syrian brag
 
RODEBLUR

RODEBLUR

moyracel
Joined
Jun 20, 2020
Posts
18,952
Reputation
18,122
Time online
65d 2h 24m
hairyballscel said:
Cumskins when ethnics and blacks have blue and green eyes:

View attachment 601166
those pictures were of eye darkening bro... they will just make them even more ethnic rofl
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
RODEBLUR said:
those pictures were of eye darkening bro... they will just make them even more ethnic rofl
read the thread again dumbass
 
RODEBLUR

RODEBLUR

moyracel
Joined
Jun 20, 2020
Posts
18,952
Reputation
18,122
Time online
65d 2h 24m
hairyballscel said:
read the thread again dumbass
so just take skin lighteners to make your eyes blue theory??? i know eye colour isn't a spectrum but rather a level, 0% melanin is grey/baby blue eyes and 100% is pitch black dark brown ones, in between is green as Stroma has covered this before but i doubt skin lighteners are gonna change your eye colour
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
TheEndHasNoEnd said:
"while transforming growth factor‐β2, interleukin‐6, and cholinergic agonists inhibit melanogenesis and/or growth of UM in vitro."
Idiot
 
D

Deleted member 6939

Zephir
Joined
May 14, 2020
Posts
1,525
Reputation
1,855
Time online
8d 20h 32m
hairyballscel said:
Latanoprost is a medicine that treats high pressure inside the eye, it is a synthetic prostaglandin analogue, which as well as naturally occurring prostaglandins such as PGF2a and PGE2, have been shown to induce increased pigmentation in the iris. Here is some examples:

View attachment 601074 View attachment 601075

The way this works is still not completely clear, but for your eyes to get darker, increased synthesis of melanin must occur....

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1771317/
- https://www.sciencedirect.com/science/article/abs/pii/S0039625797800197
Melanin is derived from the amino acid—tyrosine—through a synthesis regulated by the enzyme tyrosinase. View attachment 601101


Tyrosinase is the most important enzyme in the synthesis of melanin, many skin lighteners work by inhibiting this enzyme. Tyrosinase inhibitors include hydroquinone arbutin, kojic acid, azelaic acid, L-ascorbic acid/Vitamin C. It no suprise that the aformentioned products are some of the best substances for lightening/treating hyperpigmentation.






Now this study claims that they have a drug which blocks the synthesis of tyrosinase, it works by using alpha-methyl-p-tyrosine


This study conducted an experiment to prove the effiacy of this drug in lightening BROWN EYES:
View attachment 601115
Now the arrow points to the amount of melanin content in the cells, we can see that use of alpha.-methyl-p-tyrosine decreases mealnin content in brown eyes, even without using latanoprost(the control), so this drug could possibly be used on its own to lighten dark eyes

It also decreased tyrinoase activity which is how skin lighteners often work

Except for one row, it consistently decreased melanin production, content and tyrosinase activity

"These results show that melanin production by iris melanocytes is inhibited by alpha.-methyl-p-tyrosine."


---------------------------------------------------------------------------
Results for brown-blue eyes


View attachment 601148
This is the second part of the study and it was conducted on blue-brown eyes, it still worked to inhibit melanin production, content and tyrosinase activity, but not as well as it did for brown eyes, as you can see, there a few rows melanin production increased, but this was probaly just random fluctuation, so this is probably more effective if you have very dark eyes.



"Although the present description concerns particularly the inhibition of melanin production induced by latanoprost, alpha.-methyl-p-tyrosine can be used successfully to inhibit the same Side effect of pigmentation induced by other pharmacological treatments or metabolic imbalance of different origin."

- This means that this drug doesn't have to be used in response to eye colour change from latanoprost, so it can be used without it

The name of the drug is metyrosine and for lightening the eyes it should be dosed at 100-500mg.


TLDR - metyrosine is a drug which significantly decreases melanin production, content and tyrosinase activity, those with high concentrations of melanin in the eyes have brown eyes, very little melanin makes eyes blue.



I could be wrong about all of this, seeing as there were no pics in the study, we don't know how this would translate visually, i want a discussion and wanna see ppls opinion on this





Cumskins when ethnics and blacks have blue and green eyes:

View attachment 601166
Lanasoprost is a prostaglandin analogue

For those changes to show it would take years of use (5-10 possibly) and it only affects a small amount of people



Source: My father is an optometrist
 
Henry_Gandy

Henry_Gandy

Wizard
Joined
Jan 25, 2020
Posts
1,350
Reputation
1,861
Time online
96d 9h 27m
金木研 said:
Lanasoprost is a prostaglandin analogue

For those changes to show it would take years of use (5-10 possibly) and it only affects a small amount of people



Source: My father is an optometrist
Just take topical Moxifloxacin and some levobunolol eye drops bro...

Levobunolol is a beta-blocker and that can exacerbate vitiligo (depigmentation): https://bjo.bmj.com/content/83/12/1403.4, or maybe combine Levobunolol with DMSO as well as topical moxifloxacin. This is just the tip of the iceberg I think. Must be way more drugs that can do this both safely and really effectively
 

Attachments

  • Screen Shot 2021-02-21 at 2.52.04 pm.png
    Screen Shot 2021-02-21 at 2.52.04 pm.png
    298.3 KB · Views: 42
  • Screen Shot 2021-02-21 at 2.53.30 pm.png
    Screen Shot 2021-02-21 at 2.53.30 pm.png
    161.8 KB · Views: 43
  • Screen Shot 2021-02-21 at 2.54.15 pm.png
    Screen Shot 2021-02-21 at 2.54.15 pm.png
    345.3 KB · Views: 57
joeveniro

joeveniro

RIP Cutiegarden
Joined
Jul 28, 2020
Posts
4,619
Reputation
8,754
Time online
71d 9h 31m
Liquorice: comprável manipulável fácil, mg por gota = 333mg ( https://www.biovea.net/br/product/detail/7350/gotas-de-alcacuz-30ml/ )
/
Ácido elágico: comprável manipulável e fácil, porém é vendido por capsulas ( dissolver em água, talvez (?) ( https://www.unicpharma.com.br/pomegranate-extrato-de-roma-450mg-60-caps )
/
Piloarpina: comprável manipulável e fácil, solução em gota ( https://www.drogaosuper.com.br/Produto/101496/pilocarpina-2-10-ml-solucao)
/
Tyrosine Inhibitors disponíveis em mão: Hidroquinona, Tretinoina e fluocinolona acetonida ( os 3 são juntos em pasta; constando em ordem: 4% + 0,05% + 0,01%.

too tired to translate this shit but the english word is basically the same;
was also looking into some anti-cancer medicines that removes the melanin of the eye ( and it does effectvily removes, but has a REALLY GREAT risk to blind the eye )
 
Henry_Gandy

Henry_Gandy

Wizard
Joined
Jan 25, 2020
Posts
1,350
Reputation
1,861
Time online
96d 9h 27m
joeveniro said:
Liquorice: comprável manipulável fácil, mg por gota = 333mg ( https://www.biovea.net/br/product/detail/7350/gotas-de-alcacuz-30ml/ )
/
Ácido elágico: comprável manipulável e fácil, porém é vendido por capsulas ( dissolver em água, talvez (?) ( https://www.unicpharma.com.br/pomegranate-extrato-de-roma-450mg-60-caps )
/
Piloarpina: comprável manipulável e fácil, solução em gota ( https://www.drogaosuper.com.br/Produto/101496/pilocarpina-2-10-ml-solucao)
/
Tyrosine Inhibitors disponíveis em mão: Hidroquinona, Tretinoina e fluocinolona acetonida ( os 3 são juntos em pasta; constando em ordem: 4% + 0,05% + 0,01%.

too tired to translate this shit but the english word is basically the same;
was also looking into some anti-cancer medicines that removes the melanin of the eye ( and it does effectvily removes, but has a REALLY GREAT risk to blind the eye )
so what here exactly is safe then, also are there any before and after pics like the ones I posted for the ones I found
 
Last edited:
Stare

Stare

ㅤㅤ ‏‏‎
Joined
Feb 11, 2019
Posts
5,992
Reputation
10,068
Time online
171d 7h 28m
Bros, there is no drug to effectively lighten the iris, stop the cope.
Pharma and cosmetic industries already invested tons of money into it with top tier pharmacists and found nothing.
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
Stare said:
Bros, there is no drug to effectively lighten the iris, stop the cope.
Pharma and cosmetic industries already invested tons of money into it with top tier pharmacists and found nothing.
This is a self-improvement forum. Fuck off with you defeatist bullshit. - Stare
 
Stare

Stare

ㅤㅤ ‏‏‎
Joined
Feb 11, 2019
Posts
5,992
Reputation
10,068
Time online
171d 7h 28m
hairyballscel said:
This is a self-improvement forum. Fuck off with you defeatist bullshit. - Stare
Just being realistic
 
Stare

Stare

ㅤㅤ ‏‏‎
Joined
Feb 11, 2019
Posts
5,992
Reputation
10,068
Time online
171d 7h 28m
hairyballscel said:
you've done no research into this, i can tell
I don't think an internet forum with young guys would do a better job than actual researchers.
If anyone ever found a way to light the iris color they will become billionaires, and giant cosmetic industries invest a lot in this.
 
RAITEIII

RAITEIII

Ruleth 1
Joined
Jun 20, 2019
Posts
17,661
Reputation
18,845
Time online
211d 22h 8m
hairyballscel said:
  • Diarrhea
  • drooling
  • trembling and shaking of hands and fingers
  • trouble in speaking
  • Anxiety
  • confusion
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental depression
also ur not supposed to be driving or doing any hazardous activity as reactions could be impaired.
All drugs i take can potentially cause those side effects
 
Sal123

Sal123

Master
Joined
Oct 21, 2019
Posts
1,427
Reputation
1,144
Time online
37d 11h 30m
If taken orally it would get distorted by the salivary lipase, pancreatic lipase, and stomach acid. It can only be taken intravenously or vagina/rectum
 
hairyballscel

hairyballscel

✡︎
Joined
Feb 21, 2020
Posts
5,040
Reputation
8,813
Time online
131d 24m
Sal123 said:
If taken orally it would get distorted by the salivary lipase, pancreatic lipase, and stomach acid. It can only be taken intravenously or vagina/rectum
read the thread
 
Henry_Gandy

Henry_Gandy

Wizard
Joined
Jan 25, 2020
Posts
1,350
Reputation
1,861
Time online
96d 9h 27m
Strike_Poseidon said:
Just take topical Moxifloxacin and some levobunolol eye drops bro...

Levobunolol is a beta-blocker and that can exacerbate vitiligo (depigmentation): https://bjo.bmj.com/content/83/12/1403.4, or maybe combine Levobunolol with DMSO as well as topical moxifloxacin. This is just the tip of the iceberg I think. Must be way more drugs that can do this both safely and really effectively
Stare said:
Bros, there is no drug to effectively lighten the iris, stop the cope.
Pharma and cosmetic industries already invested tons of money into it with top tier pharmacists and found nothing.
After I literally post drugs that can do it, with photographic evidence too
 
N1c

N1c

Lost it all at 18
Joined
Feb 28, 2021
Posts
1,133
Reputation
1,475
Time online
36d 1h 35m
It should theoretically be possible to lighten your eye colour if you where born with blue eyes and have hazel, lightbrown or any eyecolour lighter then that
 
N1c

N1c

Lost it all at 18
Joined
Feb 28, 2021
Posts
1,133
Reputation
1,475
Time online
36d 1h 35m
Has anyone here made some further reaserch into this or actually tried out something? Slightly lighter eyes could ascend me a bit
 
quakociaptockh

quakociaptockh

depressed subhuman autistic hiinhib oldcel midget
Joined
Nov 9, 2020
Posts
1,775
Reputation
2,573
Time online
51d 16h 59m
hairyballscel said:
  • Diarrhea
  • drooling
  • trembling and shaking of hands and fingers
  • trouble in speaking
  • Anxiety
  • confusion
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental depression
also ur not supposed to be driving or doing any hazardous activity as reactions could be impaired.

I have all of this already so the drug can't make it any worse.
 
PikachuCandy

PikachuCandy

Thomas Anders lookalike
Joined
Aug 4, 2020
Posts
7,104
Reputation
8,290
Time online
132d 2h 17m
Where to buy
 
BUY$DRUGS

BUY$DRUGS

‎ ‏‏‎ ‎
Joined
Feb 5, 2021
Posts
1,068
Reputation
1,357
Time online
8d 16h 3m
PikachuCandy said:
Where to buy
Shits like 40 grand for one bottle
 
PikachuCandy

PikachuCandy

Thomas Anders lookalike
Joined
Aug 4, 2020
Posts
7,104
Reputation
8,290
Time online
132d 2h 17m
BUY$DRUGS said:
Shits like 40 grand for one bottle
40k for a bottle??
 
BUY$DRUGS

BUY$DRUGS

‎ ‏‏‎ ‎
Joined
Feb 5, 2021
Posts
1,068
Reputation
1,357
Time online
8d 16h 3m
PikachuCandy

PikachuCandy

Thomas Anders lookalike
Joined
Aug 4, 2020
Posts
7,104
Reputation
8,290
Time online
132d 2h 17m
BUY$DRUGS said:
Yep look that shit up
Jesus Christ
For 40k i can get all of mt surgeries covered
 

Similar threads

Won't stop mogging
Replies
50
Views
1K
LooksmaxxHopeful
LooksmaxxHopeful
.👽.
Replies
21
Views
730
PingPong
PingPong
RandomGuy
Replies
38
Views
2K
MyAssStinksLikeShit
MyAssStinksLikeShit
ageistheblackestpill
Replies
3
Views
285
PURE ARYAN GENETICS
PURE ARYAN GENETICS

Users who are viewing this thread

Top