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The Wolverine Healing Stack & NAD+ to Live Forever (Anti Ageing, Skin Health) by David Laid + my words
Peptide 1: BPC-157
"helps repair the intestinal lining, enhances the gut's microbiome, and
promotes greater balance- between the
gastrointestinal area,
nervous system, and immune.
"promotes nitric oxide
synthesis, activating cells
involved in tissue repair, stimulating the synthesis of growth factors, and inhibiting inflammation" - David Laid
BPC-157 stands for Body Protection Compound-157, a synthetic peptide-chain derived from a natural protein in human gastric juice. A number of presumptions are fastened to its potential therapeutic benefits in healing and tissue protection. Research shows that BPC 157 is helpful in accelerating the recoveries of tendons, muscles, ligaments, and gastrointestinal tract.
In terms of gastrointestinal health, BPC-157 seems very promising in the healing process in cases of injury, from ulcers and inflammatory bowel disease to leaky gut syndrome. It looks to be able to have a good effect on tissue repair while protecting from damage, partly due to its anti-inflammatory effects. How BPC-157 exerts its activity is still unknown. Nevertheless, the general hypothesis is that it would have a role in modulating growth factors, promoting angiogenesis, and regulating the expression of proteins having a vital role in tissue healing.
Most of the research on the BPC-157 peptide has been conducted on animal models—majorly rodents—with very few on human subjects. Therefore, while it holds great promise as an agent in sports medicine and in applied gastroenterological medicine, a lot more work needs to be conducted before it is safe and effective for human use. The peptide is administrated by injection, and in nearly every country worldwide, it remains unapproved for use in humans and thus mostly experimental. Further studies will have to be conducted in establishing both its wider applicability and therapeutic potential.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/
https://pubmed.ncbi.nlm.nih.gov/30915550/
Peptide 2: Thymosin-β4
"Increases healing on
a cellular level. Soft tissue repair - tendon, ligament, muscle. Helps with all sports and athletic injuries. Reduces scar tissue and may improve hair
regrowth." - David Laid
Thymosin-β4 is an endogenous peptide, native to practically all tissues and cell types of the body. Its significant activities include cellular repair, wounding, and tissue regeneration. Thymosin-β4 is known for promoting the migration of cells toward sites of injury and inflammation, thus playing a significant function in facilitating repair processes within tissues. It has potential therapeutic application in the treatment of various diseases, from cardiovascular diseases to neurological disorders and skin lesions. Some mechanisms it conducts activities on include promotion of angiogenesis, modulation of inflammation, and promotion of tissue remodeling. Though its use has been documented mainly in animal models and within experimental settings for the most part, Thymosin-β4 does show much promise as a therapeutic agent to aid in recovery enhancement and regeneration in human health applications. More studies are required to fully understand its efficiency, safety, and multiple clinical potentials in various medical disciplines.
https://pubmed.ncbi.nlm.nih.gov/22074294/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724243/
Peptide 3: GHK-Cu
"Promotes wound
healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan
synthesis in skin
fibroblasts and
promotion of blood
vessels growth" - David Laid
GHK-Cu, or Copper Peptide GHK-Cu, is one such naturally occurring peptide complex comprising a tripeptide, Glycyl-L-Histidyl-L-Lysine combined with a copper ion. It drew interest in the scientific community for study due to its various biological activities and plausible therapeutic advantages. GHK-Cu has actually already been utilized for its antioxidative properties in protecting the cells from oxidative stress and damage. It is also involved in the wound healing process by stimulating collagen and elastin production, important skin structure and elasticity proteins. Recently, GHK-Cu was shown to exert anti-inflammatory activity and be a tissue regeneration promoter in different organs. Different studies have been conducted on its possible applications: skincare, hair growth, or neurology, thus showing the huge possibilities of GHK-Cu uses in several fields of medicine. While most of the research was done on experimental models and in vitro studies, this peptide does appear to hold promise for GHK-Cu as a multifunctional peptide with clinical applications. Especially in human clinical trials, its therapeutic efficacy and safety profile will need further research.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
Most important: NAD+
"Slows Down the
Ageing Process -Boosts Your
Metabolism and Aids
Weight Loss
-Improves Mental
Clarity and Brain Power
-Beats Fatigue and
Increases Energy
-Helps to Reverse Sun Damage
-Reduces Inflammation" - David Laid
NAD+ is a coenzyme present in each living cell of an organism. It plays a huge role in biological processes, most especially those involved in energy metabolism and cellular repair. Basically, it serves as a facilitator in passing the electrons from one enzyme onto another in the occurrence of cellular respiration, ultimately converting nutrient compounds into energy. Besides the direct association it has with the energy production process, NAD+ participates in regulating important cellular activities such as DNA repair, gene expression, and mitochondrial health maintenance. It has been previously demonstrated that the levels of NAD+ decline with age and thereby contribute to a broad spectrum of diseases related to aging. As such, there is great interest in supplementation with NAD+ as an intervention for anti-aging and age-related diseases. Research also tested its potential benefit as an enhancer of mitochondrial function, improver of cognitive health, and supporter of cardiovascular function. Supplementing with NAD+, it has been widely suggested, holds key promise from preclinical and some clinical studies, but further research is needed to attain a clearer look at full efficacy, optimal dosing, and long-term effects on human health and disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
- Peptide 1: BPC-157
- Peptide 2: Thymosin-β4
- Peptide 3: GHK-Cu
- Most important: NAD+
Peptide 1: BPC-157
"helps repair the intestinal lining, enhances the gut's microbiome, and
promotes greater balance- between the
gastrointestinal area,
nervous system, and immune.
"promotes nitric oxide
synthesis, activating cells
involved in tissue repair, stimulating the synthesis of growth factors, and inhibiting inflammation" - David Laid
BPC-157 stands for Body Protection Compound-157, a synthetic peptide-chain derived from a natural protein in human gastric juice. A number of presumptions are fastened to its potential therapeutic benefits in healing and tissue protection. Research shows that BPC 157 is helpful in accelerating the recoveries of tendons, muscles, ligaments, and gastrointestinal tract.
In terms of gastrointestinal health, BPC-157 seems very promising in the healing process in cases of injury, from ulcers and inflammatory bowel disease to leaky gut syndrome. It looks to be able to have a good effect on tissue repair while protecting from damage, partly due to its anti-inflammatory effects. How BPC-157 exerts its activity is still unknown. Nevertheless, the general hypothesis is that it would have a role in modulating growth factors, promoting angiogenesis, and regulating the expression of proteins having a vital role in tissue healing.
Most of the research on the BPC-157 peptide has been conducted on animal models—majorly rodents—with very few on human subjects. Therefore, while it holds great promise as an agent in sports medicine and in applied gastroenterological medicine, a lot more work needs to be conducted before it is safe and effective for human use. The peptide is administrated by injection, and in nearly every country worldwide, it remains unapproved for use in humans and thus mostly experimental. Further studies will have to be conducted in establishing both its wider applicability and therapeutic potential.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/
https://pubmed.ncbi.nlm.nih.gov/30915550/
Peptide 2: Thymosin-β4
"Increases healing on
a cellular level. Soft tissue repair - tendon, ligament, muscle. Helps with all sports and athletic injuries. Reduces scar tissue and may improve hair
regrowth." - David Laid
Thymosin-β4 is an endogenous peptide, native to practically all tissues and cell types of the body. Its significant activities include cellular repair, wounding, and tissue regeneration. Thymosin-β4 is known for promoting the migration of cells toward sites of injury and inflammation, thus playing a significant function in facilitating repair processes within tissues. It has potential therapeutic application in the treatment of various diseases, from cardiovascular diseases to neurological disorders and skin lesions. Some mechanisms it conducts activities on include promotion of angiogenesis, modulation of inflammation, and promotion of tissue remodeling. Though its use has been documented mainly in animal models and within experimental settings for the most part, Thymosin-β4 does show much promise as a therapeutic agent to aid in recovery enhancement and regeneration in human health applications. More studies are required to fully understand its efficiency, safety, and multiple clinical potentials in various medical disciplines.
https://pubmed.ncbi.nlm.nih.gov/22074294/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724243/
Peptide 3: GHK-Cu
"Promotes wound
healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan
synthesis in skin
fibroblasts and
promotion of blood
vessels growth" - David Laid
GHK-Cu, or Copper Peptide GHK-Cu, is one such naturally occurring peptide complex comprising a tripeptide, Glycyl-L-Histidyl-L-Lysine combined with a copper ion. It drew interest in the scientific community for study due to its various biological activities and plausible therapeutic advantages. GHK-Cu has actually already been utilized for its antioxidative properties in protecting the cells from oxidative stress and damage. It is also involved in the wound healing process by stimulating collagen and elastin production, important skin structure and elasticity proteins. Recently, GHK-Cu was shown to exert anti-inflammatory activity and be a tissue regeneration promoter in different organs. Different studies have been conducted on its possible applications: skincare, hair growth, or neurology, thus showing the huge possibilities of GHK-Cu uses in several fields of medicine. While most of the research was done on experimental models and in vitro studies, this peptide does appear to hold promise for GHK-Cu as a multifunctional peptide with clinical applications. Especially in human clinical trials, its therapeutic efficacy and safety profile will need further research.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
Most important: NAD+
"Slows Down the
Ageing Process -Boosts Your
Metabolism and Aids
Weight Loss
-Improves Mental
Clarity and Brain Power
-Beats Fatigue and
Increases Energy
-Helps to Reverse Sun Damage
-Reduces Inflammation" - David Laid
NAD+ is a coenzyme present in each living cell of an organism. It plays a huge role in biological processes, most especially those involved in energy metabolism and cellular repair. Basically, it serves as a facilitator in passing the electrons from one enzyme onto another in the occurrence of cellular respiration, ultimately converting nutrient compounds into energy. Besides the direct association it has with the energy production process, NAD+ participates in regulating important cellular activities such as DNA repair, gene expression, and mitochondrial health maintenance. It has been previously demonstrated that the levels of NAD+ decline with age and thereby contribute to a broad spectrum of diseases related to aging. As such, there is great interest in supplementation with NAD+ as an intervention for anti-aging and age-related diseases. Research also tested its potential benefit as an enhancer of mitochondrial function, improver of cognitive health, and supporter of cardiovascular function. Supplementing with NAD+, it has been widely suggested, holds key promise from preclinical and some clinical studies, but further research is needed to attain a clearer look at full efficacy, optimal dosing, and long-term effects on human health and disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/
https://pubmed.ncbi.nlm.nih.gov/30915550/
https://pubmed.ncbi.nlm.nih.gov/22074294/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724243/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
His words from his stories
https://pubmed.ncbi.nlm.nih.gov/30915550/
https://pubmed.ncbi.nlm.nih.gov/22074294/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724243/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508379/
His words from his stories
